Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19)

This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:48

Enthalten in:

The American journal of Chinese medicine - 48(2020), 7 vom: 08., Seite 1523-1538

Sprache:

Englisch

Beteiligte Personen:

Shi, Jia [VerfasserIn]
Lu, Yunfei [VerfasserIn]
Zhang, Yuan [VerfasserIn]
Xia, Lu [VerfasserIn]
Ye, Chen [VerfasserIn]
Lü, Ying [VerfasserIn]
Chen, Shishi [VerfasserIn]
Xu, Qingnian [VerfasserIn]
Tang, Bozong [VerfasserIn]
Yin, Keshan [VerfasserIn]
Zhang, Jing [VerfasserIn]
Chen, Xiaorong [VerfasserIn]
Yang, Zongguo [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Clinical Study
Coronavirus
Decoction
Drugs, Chinese Herbal
Formulation
Herbs
Journal Article
SARS-CoV-2
Traditional Chinese Medicine

Anmerkungen:

Date Completed 21.12.2020

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1142/S0192415X20500755

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM317162160