Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19)
This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2020 |
---|---|
Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:48 |
---|---|
Enthalten in: |
The American journal of Chinese medicine - 48(2020), 7 vom: 08., Seite 1523-1538 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Shi, Jia [VerfasserIn] |
---|
Links: |
---|
Themen: |
COVID-19 |
---|
Anmerkungen: |
Date Completed 21.12.2020 Date Revised 07.12.2022 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1142/S0192415X20500755 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM317162160 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM317162160 | ||
003 | DE-627 | ||
005 | 20231225162647.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2020 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1142/S0192415X20500755 |2 doi | |
028 | 5 | 2 | |a pubmed24n1057.xml |
035 | |a (DE-627)NLM317162160 | ||
035 | |a (NLM)33148005 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Shi, Jia |e verfasserin |4 aut | |
245 | 1 | 0 | |a Traditional Chinese Medicine Formulation Therapy in the Treatment of Coronavirus Disease 2019 (COVID-19) |
264 | 1 | |c 2020 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 21.12.2020 | ||
500 | |a Date Revised 07.12.2022 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a This study aimed to investigate the efficacy of Traditional Chinese Medicine (TCM) decoction with different intervention timepoints in the treatment of coronavirus disease 2019 (COVID-19) patients. We retrospectively collected the medical records and evaluated the outcomes of COVID-19 patients that received TCM decoction treatment at different timepoints. A total of 234 COVID-19 patients were included in this study. Patients who received TCM decoction therapy within 3 days or 7 days after admission could achieve shorter hospitalization days and disease periods compared to those who received TCM decoction [Formula: see text] 7 days after admission (all [Formula: see text]). Patients who received TCM decoction therapy within 3 days had significantly fewer days to negative SARS-CoV-2 from nasopharyngeal/oral swab and days to negative SARS-CoV-2 from urine/stool/blood samples compared to those received TCM decoction [Formula: see text] days after admission (all [Formula: see text]). Patients who received TCM decoction therapy on the 3rd to 7th day after admission had a faster achievement of negative SARS-CoV-2 from urine/stool/blood samples compared to those who received TCM decoction [Formula: see text] days after admission ([Formula: see text]). Logistic models revealed that more days from TCM decoction to admission [Formula: see text] days might be a risk factor for long hospitalization days, disease period, and slower negative-conversion of SARS-CoV-2 (all [Formula: see text]). Conclusively, our results suggest that TCM decoction therapy should be considered at the early stage of COVID-19 patients | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a COVID-19 | |
650 | 4 | |a Clinical Study | |
650 | 4 | |a Coronavirus | |
650 | 4 | |a Decoction | |
650 | 4 | |a Formulation | |
650 | 4 | |a Herbs | |
650 | 4 | |a SARS-CoV-2 | |
650 | 4 | |a Traditional Chinese Medicine | |
650 | 7 | |a Drugs, Chinese Herbal |2 NLM | |
700 | 1 | |a Lu, Yunfei |e verfasserin |4 aut | |
700 | 1 | |a Zhang, Yuan |e verfasserin |4 aut | |
700 | 1 | |a Xia, Lu |e verfasserin |4 aut | |
700 | 1 | |a Ye, Chen |e verfasserin |4 aut | |
700 | 1 | |a Lü, Ying |e verfasserin |4 aut | |
700 | 1 | |a Chen, Shishi |e verfasserin |4 aut | |
700 | 1 | |a Xu, Qingnian |e verfasserin |4 aut | |
700 | 1 | |a Tang, Bozong |e verfasserin |4 aut | |
700 | 1 | |a Yin, Keshan |e verfasserin |4 aut | |
700 | 1 | |a Zhang, Jing |e verfasserin |4 aut | |
700 | 1 | |a Chen, Xiaorong |e verfasserin |4 aut | |
700 | 1 | |a Yang, Zongguo |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t The American journal of Chinese medicine |d 1993 |g 48(2020), 7 vom: 08., Seite 1523-1538 |w (DE-627)NLM000457817 |x 1793-6853 |7 nnns |
773 | 1 | 8 | |g volume:48 |g year:2020 |g number:7 |g day:08 |g pages:1523-1538 |
856 | 4 | 0 | |u http://dx.doi.org/10.1142/S0192415X20500755 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 48 |j 2020 |e 7 |b 08 |h 1523-1538 |