Kawasaki disease presenting with hoarseness : A multinational study of the REKAMLATINA network
© 2020 Japan Pediatric Society..
BACKGROUND: Recently, hoarseness affecting the supraglottic structure has been reported in Kawasaki disease (KD). The objective of this study was to characterize the frequency of hoarseness in acute KD patients in Latin America.
METHODS: We used prospective data from the multinational Red de Enfermedad de Kawasaki en America Latina (REKAMLATINA) network. A total of 865 patients from 20 countries were enrolled during the 3 year study period. Data on hoarseness were available in 858 (99.2%) patients. The clinical and laboratory characteristics between hoarse and non-hoarse KD were compared.
RESULTS: Hoarseness was documented in 100 (11.6%) patients. Hoarse patients were younger than those with KD without hoarseness (median age 18 vs 26 months; P = 0.002) and presented with lower hemoglobin (10.7 g/dL vs 11.3 g/dL; P = 0.040) and hematocrit levels (32% vs 33%, P = 0.048).
CONCLUSIONS: Hoarseness was found to be prevalent as a presenting sign of acute KD in younger children. Anemia may indicate the presence of active inflammation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:63 |
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| Enthalten in: |
Pediatrics international : official journal of the Japan Pediatric Society - 63(2021), 6 vom: 01. Juni, Seite 643-648 |
| Sprache: |
Englisch |
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| Links: |
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| Themen: |
Child |
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| Anmerkungen: |
Date Completed 18.08.2021 Date Revised 18.08.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/ped.14521 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316686794 |
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| 100 | 1 | |a Gámez-González, Luisa B |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Kawasaki disease presenting with hoarseness |b A multinational study of the REKAMLATINA network |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
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| 500 | |a Date Completed 18.08.2021 | ||
| 500 | |a Date Revised 18.08.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 Japan Pediatric Society. | ||
| 520 | |a BACKGROUND: Recently, hoarseness affecting the supraglottic structure has been reported in Kawasaki disease (KD). The objective of this study was to characterize the frequency of hoarseness in acute KD patients in Latin America | ||
| 520 | |a METHODS: We used prospective data from the multinational Red de Enfermedad de Kawasaki en America Latina (REKAMLATINA) network. A total of 865 patients from 20 countries were enrolled during the 3 year study period. Data on hoarseness were available in 858 (99.2%) patients. The clinical and laboratory characteristics between hoarse and non-hoarse KD were compared | ||
| 520 | |a RESULTS: Hoarseness was documented in 100 (11.6%) patients. Hoarse patients were younger than those with KD without hoarseness (median age 18 vs 26 months; P = 0.002) and presented with lower hemoglobin (10.7 g/dL vs 11.3 g/dL; P = 0.040) and hematocrit levels (32% vs 33%, P = 0.048) | ||
| 520 | |a CONCLUSIONS: Hoarseness was found to be prevalent as a presenting sign of acute KD in younger children. Anemia may indicate the presence of active inflammation | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Kawasaki disease | |
| 650 | 4 | |a Latin American | |
| 650 | 4 | |a child | |
| 650 | 4 | |a hoarseness | |
| 650 | 7 | |a Hemoglobins |2 NLM | |
| 700 | 1 | |a Ulloa-Gutierrez, Rolando |e verfasserin |4 aut | |
| 700 | 1 | |a Murata, Chiharu |e verfasserin |4 aut | |
| 700 | 1 | |a Yamazaki-Nakashimada, Marco A |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Elissa |e verfasserin |4 aut | |
| 700 | 1 | |a Estripeaut, Dora |e verfasserin |4 aut | |
| 700 | 1 | |a Del Águila, Olguita |e verfasserin |4 aut | |
| 700 | 1 | |a Garrido-García, Luis M |e verfasserin |4 aut | |
| 700 | 1 | |a Gómez, Virgen |e verfasserin |4 aut | |
| 700 | 1 | |a Faugier-Fuentes, Enrique |e verfasserin |4 aut | |
| 700 | 1 | |a Miño, Greta |e verfasserin |4 aut | |
| 700 | 1 | |a Beltrán, Sandra |e verfasserin |4 aut | |
| 700 | 1 | |a Cofré, Fernanda |e verfasserin |4 aut | |
| 700 | 1 | |a Chacón-Cruz, Enrique |e verfasserin |4 aut | |
| 700 | 1 | |a Saltigeral-Simental, Patricia |e verfasserin |4 aut | |
| 700 | 1 | |a Martínez-Medina, Lucila |e verfasserin |4 aut | |
| 700 | 1 | |a Tremoulet, Adriana H |e verfasserin |4 aut | |
| 700 | 0 | |a Kawasaki Disease REKAMLATINA Network |e verfasserin |4 aut | |
| 700 | 1 | |a Astigarraga, Norma |e verfasserin |4 aut | |
| 700 | 1 | |a Borzutzky, Arturo |e investigator |4 oth | |
| 700 | 1 | |a Passos, Saulo Duarte |e investigator |4 oth | |
| 700 | 1 | |a Gutierrez, Stella |e investigator |4 oth | |
| 700 | 1 | |a Bernal-Granillo, Sergio |e investigator |4 oth | |
| 700 | 1 | |a Dueñas, Lourdes |e investigator |4 oth | |
| 700 | 1 | |a Álvarez-Olmos, Martha I |e investigator |4 oth | |
| 700 | 1 | |a Pérez-Camacho, Pahola |e investigator |4 oth | |
| 700 | 1 | |a Collia, Adrián |e investigator |4 oth | |
| 700 | 1 | |a Arbo, Antonio |e investigator |4 oth | |
| 700 | 1 | |a Vázquez-Narváez, Jorge A |e investigator |4 oth | |
| 700 | 1 | |a López-Medina, Eduardo |e investigator |4 oth | |
| 700 | 1 | |a Zaidi, Mussaret B |e investigator |4 oth | |
| 700 | 1 | |a Viviani, Tamara |e investigator |4 oth | |
| 700 | 1 | |a Luque, Marco T |e investigator |4 oth | |
| 700 | 1 | |a Rodríguez-Quiroz, Francisco J |e investigator |4 oth | |
| 700 | 1 | |a Grazioso, Carlos F |e investigator |4 oth | |
| 700 | 1 | |a de Sousa Marques, Heloisa Helena |e investigator |4 oth | |
| 700 | 1 | |a Luciani, Kathia |e investigator |4 oth | |
| 700 | 1 | |a Zambrano, Mildred |e investigator |4 oth | |
| 700 | 1 | |a Melgar, Mario |e investigator |4 oth | |
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| 700 | 1 | |a Avila-Agüero Ml, María L |e investigator |4 oth | |
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| 700 | 1 | |a Soriano-Fallas, Alejandra |e investigator |4 oth | |
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