Fabrication of titanium based biphasic scaffold using selective laser melting and collagen immersion
Copyright: © 2017 Sing, et al..
Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 c ollagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting and collagen infiltration. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:3 |
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| Enthalten in: |
International journal of bioprinting - 3(2017), 1 vom: 13., Seite 007 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sing, Swee Leong [VerfasserIn] |
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| Links: |
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| Themen: |
Biphasic scaffolds |
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| Anmerkungen: |
Date Revised 24.10.2020 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.18063/IIB.2017.01.007 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316630705 |
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| 520 | |a Copyright: © 2017 Sing, et al. | ||
| 520 | |a Tissue engineering approaches have been adopted to address challenges in osteochondral tissue regeneration. Single phase scaffolds, which consist of only one single material throughout the whole structure, have been used extensively in these tissue engineering approaches. However, a single phase scaffold is insufficient in providing all the properties required for regeneration and repair of osteochondral defects. Biphasic scaffolds with two distinct phases of titanium/type 1 c ollagen and titanium-tantalum/type 1 collagen were developed for the first time using selective laser melting and collagen infiltration. Observation of the biphasic scaffolds demonstrated continuous interface between the two phases and mechanical characterization of the metallic scaffolds support the feasibility of the newly developed scaffolds for tissue engineering in osteochondral defects | ||
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| 700 | 1 | |a Ha, Thi Mai Hoa |e verfasserin |4 aut | |
| 700 | 1 | |a Yeong, Wai Yee |e verfasserin |4 aut | |
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