Recurrent Stevens-Johnson syndrome in a patient with systemic lupus erythematosus : a case report
Systemic lupus erythematosus (SLE) is a systemic disease that affects many organs. A few patients with SLE develop Stevens-Johnson syndrome (SJS), a life-threatening disease characterized by the appearance of a partial-thickness burn in the skin and mucous membranes. This report aims to increase awareness among clinicians about the relationship between SLE and SJS. An 18-year-old man was admitted to the rheumatology department of Omdurman Military Hospital with a skin rash that was preceded by symptoms of a short febrile illness. He had a maculopapular rash on his palms, soles, trunk, and mucous membranes. The patient had been diagnosed with SLE at 10 years of age and had had SJS three times since the diagnosis of SLE. Investigations to exclude other diagnoses were conducted, and a skin biopsy showed features consistent with early SJS. The patient received intravenous hydrocortisone, oral prednisolone, and oral acyclovir. The lesions resolved 3 weeks after treatment with acyclovir and he was discharged in good condition. A young patient with SLE and recurrent SJS with no immunodeficiency responded very well to the conventional SJS therapy after 3 weeks of treatment.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:48 |
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| Enthalten in: |
The Journal of international medical research - 48(2020), 10 vom: 17. Okt., Seite 300060520964348 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ahmed Eltahir, Noha Ibrahim [VerfasserIn] |
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| Links: |
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| Themen: |
Autoimmune disorder |
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| Anmerkungen: |
Date Completed 14.05.2021 Date Revised 14.05.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.1177/0300060520964348 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316558893 |
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| 500 | |a Date Revised 14.05.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Systemic lupus erythematosus (SLE) is a systemic disease that affects many organs. A few patients with SLE develop Stevens-Johnson syndrome (SJS), a life-threatening disease characterized by the appearance of a partial-thickness burn in the skin and mucous membranes. This report aims to increase awareness among clinicians about the relationship between SLE and SJS. An 18-year-old man was admitted to the rheumatology department of Omdurman Military Hospital with a skin rash that was preceded by symptoms of a short febrile illness. He had a maculopapular rash on his palms, soles, trunk, and mucous membranes. The patient had been diagnosed with SLE at 10 years of age and had had SJS three times since the diagnosis of SLE. Investigations to exclude other diagnoses were conducted, and a skin biopsy showed features consistent with early SJS. The patient received intravenous hydrocortisone, oral prednisolone, and oral acyclovir. The lesions resolved 3 weeks after treatment with acyclovir and he was discharged in good condition. A young patient with SLE and recurrent SJS with no immunodeficiency responded very well to the conventional SJS therapy after 3 weeks of treatment | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Maculopapular rash | |
| 650 | 4 | |a Stevens-Johnson syndrome | |
| 650 | 4 | |a autoimmune disorder | |
| 650 | 4 | |a fever | |
| 650 | 4 | |a recurrent | |
| 650 | 4 | |a systemic lupus erythematosus | |
| 700 | 1 | |a Elgenaid, Shaima N |e verfasserin |4 aut | |
| 700 | 1 | |a Adam Essa, Mohammed Elmujtba |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmed, Abdelkareem A |e verfasserin |4 aut | |
| 700 | 1 | |a Sati Mohamed, Ayman Sati |e verfasserin |4 aut | |
| 700 | 1 | |a Ali Hussein, Mustafa Mohammed |e verfasserin |4 aut | |
| 700 | 1 | |a Abubaker, Azza |e verfasserin |4 aut | |
| 700 | 1 | |a Mohamed Elsayed, Elnazir |e verfasserin |4 aut | |
| 700 | 1 | |a Mohammed Ibrahim, Sulafa Eisa |e verfasserin |4 aut | |
| 700 | 1 | |a Mohamed Ibrahim, Osman |e verfasserin |4 aut | |
| 700 | 1 | |a Mohammed Elagib, Elnour |e verfasserin |4 aut | |
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