Biobanking for COVID-19 research
BACKGROUND: Biobanks are imperative infrastructures, particularly during outbreaks, when there is an obligation to acquire and share knowledge as quick as possible to allow for implementation of science-based preventive, diagnostic, prognostic, and therapeutic strategies.
METHODS: We established a COVID-19 biobank with the aim of collecting high-quality and well-annotated human biospecimens, in the effort to understand the pathogenic mechanisms underlying COVID-19 and identify therapeutic targets (COVID-BioB, NCT04318366). Here we describe our experience and briefly review the characteristics of the biobanks for COVID-19 that have been so far established.
RESULTS: A total of 46,677 samples have been collected from 913 participants (63.3% males, median [IQR] age 62.2 [51.2-74.0] years) since the beginning of the program. Most patients (66.9%) had been admitted to hospital for COVID-19, with a median length of stay of 15.0 (9.0-27.0) days. A minority of patients (13.3% of the total) had been admitted for other reasons and subsequently tested positive for SARS-CoV-2. The remainder were managed at home after being seen at the Emergency Department.
CONCLUSIONS: Having a solid research infrastructure already in place, along with flexibility and adaptability to new requirements, allowed for the quick building of a COVID-19 biobank that will help expand and share the knowledge of SARS-CoV-2.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:64 |
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Enthalten in: |
Panminerva medica - 64(2022), 2 vom: 04. Juni, Seite 244-252 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Rovere-Querini, Patrizia [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 12.07.2022 Date Revised 12.07.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.23736/S0031-0808.20.04168-3 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM316429805 |
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520 | |a BACKGROUND: Biobanks are imperative infrastructures, particularly during outbreaks, when there is an obligation to acquire and share knowledge as quick as possible to allow for implementation of science-based preventive, diagnostic, prognostic, and therapeutic strategies | ||
520 | |a METHODS: We established a COVID-19 biobank with the aim of collecting high-quality and well-annotated human biospecimens, in the effort to understand the pathogenic mechanisms underlying COVID-19 and identify therapeutic targets (COVID-BioB, NCT04318366). Here we describe our experience and briefly review the characteristics of the biobanks for COVID-19 that have been so far established | ||
520 | |a RESULTS: A total of 46,677 samples have been collected from 913 participants (63.3% males, median [IQR] age 62.2 [51.2-74.0] years) since the beginning of the program. Most patients (66.9%) had been admitted to hospital for COVID-19, with a median length of stay of 15.0 (9.0-27.0) days. A minority of patients (13.3% of the total) had been admitted for other reasons and subsequently tested positive for SARS-CoV-2. The remainder were managed at home after being seen at the Emergency Department | ||
520 | |a CONCLUSIONS: Having a solid research infrastructure already in place, along with flexibility and adaptability to new requirements, allowed for the quick building of a COVID-19 biobank that will help expand and share the knowledge of SARS-CoV-2 | ||
650 | 4 | |a Journal Article | |
700 | 1 | |a Tresoldi, Cristina |e verfasserin |4 aut | |
700 | 1 | |a Conte, Caterina |e verfasserin |4 aut | |
700 | 1 | |a Ruggeri, Annalisa |e verfasserin |4 aut | |
700 | 1 | |a Ghezzi, Silvia |e verfasserin |4 aut | |
700 | 1 | |a DE Lorenzo, Rebecca |e verfasserin |4 aut | |
700 | 1 | |a DI Filippo, Luigi |e verfasserin |4 aut | |
700 | 1 | |a Farina, Nicola |e verfasserin |4 aut | |
700 | 1 | |a Ramirez, Giuseppe A |e verfasserin |4 aut | |
700 | 1 | |a Ripa, Marco |e verfasserin |4 aut | |
700 | 1 | |a Mancini, Nicasio |e verfasserin |4 aut | |
700 | 1 | |a Cantarelli, Elisa |e verfasserin |4 aut | |
700 | 1 | |a Galli, Laura |e verfasserin |4 aut | |
700 | 1 | |a Poli, Andrea |e verfasserin |4 aut | |
700 | 1 | |a DE Cobelli, Francesco |e verfasserin |4 aut | |
700 | 1 | |a Bonini, Chiara |e verfasserin |4 aut | |
700 | 1 | |a Manfredi, Angelo A |e verfasserin |4 aut | |
700 | 1 | |a Franchini, Stefano |e verfasserin |4 aut | |
700 | 1 | |a Spessot, Marzia |e verfasserin |4 aut | |
700 | 1 | |a Carlucci, Michele |e verfasserin |4 aut | |
700 | 1 | |a Dagna, Lorenzo |e verfasserin |4 aut | |
700 | 1 | |a Scarpellini, Paolo |e verfasserin |4 aut | |
700 | 1 | |a Ambrosio, Alberto |e verfasserin |4 aut | |
700 | 1 | |a DI Napoli, Davide |e verfasserin |4 aut | |
700 | 1 | |a Bosi, Emanuele |e verfasserin |4 aut | |
700 | 1 | |a Tresoldi, Moreno |e verfasserin |4 aut | |
700 | 1 | |a Lazzarin, Adriano |e verfasserin |4 aut | |
700 | 1 | |a Landoni, Giovanni |e verfasserin |4 aut | |
700 | 1 | |a Martino, Gianvito |e verfasserin |4 aut | |
700 | 1 | |a Zangrillo, Alberto |e verfasserin |4 aut | |
700 | 1 | |a Poli, Guido |e verfasserin |4 aut | |
700 | 1 | |a Castagna, Antonella |e verfasserin |4 aut | |
700 | 1 | |a Vicenzi, Elisa |e verfasserin |4 aut | |
700 | 1 | |a Clementi, Massimo |e verfasserin |4 aut | |
700 | 1 | |a Ciceri, Fabio |e verfasserin |4 aut | |
700 | 0 | |a COVID-BioB Study Group |e verfasserin |4 aut | |
700 | 1 | |a Ambrosio, Alberto |e investigator |4 oth | |
700 | 1 | |a Avino, Monica |e investigator |4 oth | |
700 | 1 | |a Bargiggia, Cinzia |e investigator |4 oth | |
700 | 1 | |a Battista, Marco |e investigator |4 oth | |
700 | 1 | |a Betti, Paolo |e investigator |4 oth | |
700 | 1 | |a Bettinelli, Giulia |e investigator |4 oth | |
700 | 1 | |a Bonaldi, Filippo |e investigator |4 oth | |
700 | 1 | |a Bonini, Chiara |e investigator |4 oth | |
700 | 1 | |a Bosi, Emanuele |e investigator |4 oth | |
700 | 1 | |a Brambilla, Elena |e investigator |4 oth | |
700 | 1 | |a Bucci, Romina |e investigator |4 oth | |
700 | 1 | |a Bussolari, Cecilia |e investigator |4 oth | |
700 | 1 | |a Caccia, Roberta |e investigator |4 oth | |
700 | 1 | |a Cantarelli, Elisa |e investigator |4 oth | |
700 | 1 | |a Canti, Valentina |e investigator |4 oth | |
700 | 1 | |a Carlucci, Michele |e investigator |4 oth | |
700 | 1 | |a Casanova, Paola |e investigator |4 oth | |
700 | 1 | |a Castagna, Antonella |e investigator |4 oth | |
700 | 1 | |a Ciceri, Fabio |e investigator |4 oth | |
700 | 1 | |a Clementi, Massimo |e investigator |4 oth | |
700 | 1 | |a Conte, Caterina |e investigator |4 oth | |
700 | 1 | |a Contu, Sara |e investigator |4 oth | |
700 | 1 | |a D'Amico, Marta |e investigator |4 oth | |
700 | 1 | |a Dagna, Lorenzo |e investigator |4 oth | |
700 | 1 | |a DE Cobelli, Francesco |e investigator |4 oth | |
700 | 1 | |a DE Lalla, Claudia |e investigator |4 oth | |
700 | 1 | |a DE Lorenzo, Rebecca |e investigator |4 oth | |
700 | 1 | |a Della Valle, Patrizia |e investigator |4 oth | |
700 | 1 | |a Delmastro, Elena |e investigator |4 oth | |
700 | 1 | |a DI Biase, Carlo |e investigator |4 oth | |
700 | 1 | |a DI Filippo, Luigi |e investigator |4 oth | |
700 | 1 | |a DI Napoli, Davide |e investigator |4 oth | |
700 | 1 | |a Dumea, Iulia |e investigator |4 oth | |
700 | 1 | |a Fabbella, Lorena |e investigator |4 oth | |
700 | 1 | |a Farina, Nicola |e investigator |4 oth | |
700 | 1 | |a Finardi, Annamaria |e investigator |4 oth | |
700 | 1 | |a Franchini, Stefano |e investigator |4 oth | |
700 | 1 | |a Galli, Laura |e investigator |4 oth | |
700 | 1 | |a Ghezzi, Silvia |e investigator |4 oth | |
700 | 1 | |a Gorgoni, Francesca |e investigator |4 oth | |
700 | 1 | |a Granata, Lucio |e investigator |4 oth | |
700 | 1 | |a Grassi, Stefano |e investigator |4 oth | |
700 | 1 | |a Grazioli Moretti, Alessio |e investigator |4 oth | |
700 | 1 | |a Grossi, Michela |e investigator |4 oth | |
700 | 1 | |a Grosso, Domenico |e investigator |4 oth | |
700 | 1 | |a Landoni, Giovanni |e investigator |4 oth | |
700 | 1 | |a Lanzani, Chiara |e investigator |4 oth | |
700 | 1 | |a Lazzarin, Adriano |e investigator |4 oth | |
700 | 1 | |a Lo Raso, Giuseppe |e investigator |4 oth | |
700 | 1 | |a Maggioni, Chiara |e investigator |4 oth | |
700 | 1 | |a Magni, Giulia |e investigator |4 oth | |
700 | 1 | |a Malnati, Mauro |e investigator |4 oth | |
700 | 1 | |a Mancini, Nicasio |e investigator |4 oth | |
700 | 1 | |a Manenti, Fabio |e investigator |4 oth | |
700 | 1 | |a Manfredi, Angelo A |e investigator |4 oth | |
700 | 1 | |a Marabelli, Giuseppina |e investigator |4 oth | |
700 | 1 | |a Martino, Gianvito |e investigator |4 oth | |
700 | 1 | |a Maugeri, Norma |e investigator |4 oth | |
700 | 1 | |a Mazzoleni, Marta |e investigator |4 oth | |
700 | 1 | |a Melzi, Raffaella |e investigator |4 oth | |
700 | 1 | |a Mercalli, Alessia |e investigator |4 oth | |
700 | 1 | |a Muzio, Luca |e investigator |4 oth | |
700 | 1 | |a Noviello, Maddalena |e investigator |4 oth | |
700 | 1 | |a Pagani, Isabel |e investigator |4 oth | |
700 | 1 | |a Pagani, Nadia |e investigator |4 oth | |
700 | 1 | |a Pastori, Claudia |e investigator |4 oth | |
700 | 1 | |a Pisciali, Matteo |e investigator |4 oth | |
700 | 1 | |a Poli, Andrea |e investigator |4 oth | |
700 | 1 | |a Poli, Guido |e investigator |4 oth | |
700 | 1 | |a Ramirez, Giuseppe A |e investigator |4 oth | |
700 | 1 | |a Ripa, Marco |e investigator |4 oth | |
700 | 1 | |a Rovere-Querini, Patrizia |e investigator |4 oth | |
700 | 1 | |a Ruggeri, Annalisa |e investigator |4 oth | |
700 | 1 | |a Salvato, Damiano |e investigator |4 oth | |
700 | 1 | |a Santoleri, Luca |e investigator |4 oth | |
700 | 1 | |a Scarpellini, Paolo |e investigator |4 oth | |
700 | 1 | |a Sironi, Francesca |e investigator |4 oth | |
700 | 1 | |a Sofia, Valentina |e investigator |4 oth | |
700 | 1 | |a Spessot, Marzia |e investigator |4 oth | |
700 | 1 | |a Tassi, Elena |e investigator |4 oth | |
700 | 1 | |a Tomasi, Serenesse |e investigator |4 oth | |
700 | 1 | |a Tresoldi, Cristina |e investigator |4 oth | |
700 | 1 | |a Tresoldi, Moreno |e investigator |4 oth | |
700 | 1 | |a Vicenzi, Elisa |e investigator |4 oth | |
700 | 1 | |a Zangrillo, Alberto |e investigator |4 oth | |
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