Effect of Femtosecond Laser in Situ Keratomileusis on the Choriocapillaris Perfusion and Choroidal Thickness in Myopic Patients
PURPOSE: To investigate changes in choriocapillaris vascular density (CCD) and choroidal thickness (CT) after femtosecond laser in situ keratomileusis (FS-LASIK) in myopic patients.
METHODS: Prospective and observational self-control study. We enrolled 41 myopic patients (41 right eyes), without other ophthalmic or systemic diseases who were eligible and about to FS-LASIK surgery. The CCD was measured in the central 1-mm-diameter circle region of the macular fovea (CCD1) and the 1- to 3-mm ring-like region of the fovea (CCD1-3). The CT was measured at the fovea and at distances of 0.5 and 2.5 mm for the following: nasal, temporal, superior, and inferior to the fovea. Both were measured by optical coherence tomography angiography (OCTA) preoperatively as the baseline and at 1 day, 1 week, 1 month, and 3 months postoperatively.
RESULTS: CCD1 and CCD1-3 were significantly lower postoperatively compared with baseline. When the trough was reached, CCD1 declined by 1.51%, and CCD1-3 declined by 1.00% at 1 day postoperatively. However, then they increased with time. CCD1 recovered to baseline at 1 month postoperatively, while CCD1-3 was still lower at the end of follow-up. In addition, the CT was significantly thicker postoperatively and recovered to the baseline at 3 months postoperatively. There was no obvious correlation between CCD, CT, and other parameters.
CONCLUSIONS: The CCD decreased while the CT increased following FS-LASIK in myopic patients. However, these changes may be a temporary stress response rather than real irreversible injury to the choroid.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
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| Enthalten in: |
Current eye research - 46(2021), 6 vom: 14. Juni, Seite 878-884 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Xu, Zhiqiang [VerfasserIn] |
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| Links: |
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| Themen: |
Choriocapillaris perfusion |
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| Anmerkungen: |
Date Completed 31.12.2021 Date Revised 31.12.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/02713683.2020.1833350 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316240397 |
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| 245 | 1 | 0 | |a Effect of Femtosecond Laser in Situ Keratomileusis on the Choriocapillaris Perfusion and Choroidal Thickness in Myopic Patients |
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| 500 | |a Date Completed 31.12.2021 | ||
| 500 | |a Date Revised 31.12.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: To investigate changes in choriocapillaris vascular density (CCD) and choroidal thickness (CT) after femtosecond laser in situ keratomileusis (FS-LASIK) in myopic patients | ||
| 520 | |a METHODS: Prospective and observational self-control study. We enrolled 41 myopic patients (41 right eyes), without other ophthalmic or systemic diseases who were eligible and about to FS-LASIK surgery. The CCD was measured in the central 1-mm-diameter circle region of the macular fovea (CCD1) and the 1- to 3-mm ring-like region of the fovea (CCD1-3). The CT was measured at the fovea and at distances of 0.5 and 2.5 mm for the following: nasal, temporal, superior, and inferior to the fovea. Both were measured by optical coherence tomography angiography (OCTA) preoperatively as the baseline and at 1 day, 1 week, 1 month, and 3 months postoperatively | ||
| 520 | |a RESULTS: CCD1 and CCD1-3 were significantly lower postoperatively compared with baseline. When the trough was reached, CCD1 declined by 1.51%, and CCD1-3 declined by 1.00% at 1 day postoperatively. However, then they increased with time. CCD1 recovered to baseline at 1 month postoperatively, while CCD1-3 was still lower at the end of follow-up. In addition, the CT was significantly thicker postoperatively and recovered to the baseline at 3 months postoperatively. There was no obvious correlation between CCD, CT, and other parameters | ||
| 520 | |a CONCLUSIONS: The CCD decreased while the CT increased following FS-LASIK in myopic patients. However, these changes may be a temporary stress response rather than real irreversible injury to the choroid | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Choriocapillaris perfusion | |
| 650 | 4 | |a Choroidal thickness | |
| 650 | 4 | |a FS-LASIK | |
| 650 | 4 | |a myopic | |
| 650 | 4 | |a vascular density | |
| 700 | 1 | |a Gui, Sifeng |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Jianle |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yuan |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Fan |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Liang |e verfasserin |4 aut | |
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