Congenital syphilis : Missed opportunities and the case for rescreening during pregnancy and at delivery
© 2020 The Authors. Published by Elsevier Ltd..
Two infants treated for syphilis born to at risk mothers who screened negative at their first prenatal visit but were not rescreened at delivery are described. The first presented with classic, but unrecognized, features of congenital syphilis. In the second case, possible early maternal syphilis was diagnosed soon after delivery using the treponemal first reverse-screening algorithm. Although the child's physical exam was normal and the maternal rapid plasma reagin (RPR) negative, the child was treated for syphilis because maternal confirmatory treponemal tests suggested recent seroconversion. Given the re-emergence of congenital syphilis, our report aims to demonstrate the importance of rescreening women at increased risk and improve awareness of common manifestations of the syphilis disease in the newborn. For women at increased risk, repeat syphilis testing early in the third trimester and again at delivery in communities and populations with a high prevalence of syphilis is recommended.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
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| Enthalten in: |
IDCases - 22(2020) vom: 15., Seite e00964 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
O'Connor, Nicola P [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 29.03.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.idcr.2020.e00964 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM315948779 |
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| 245 | 1 | 0 | |a Congenital syphilis |b Missed opportunities and the case for rescreening during pregnancy and at delivery |
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| 500 | |a Date Revised 29.03.2024 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2020 The Authors. Published by Elsevier Ltd. | ||
| 520 | |a Two infants treated for syphilis born to at risk mothers who screened negative at their first prenatal visit but were not rescreened at delivery are described. The first presented with classic, but unrecognized, features of congenital syphilis. In the second case, possible early maternal syphilis was diagnosed soon after delivery using the treponemal first reverse-screening algorithm. Although the child's physical exam was normal and the maternal rapid plasma reagin (RPR) negative, the child was treated for syphilis because maternal confirmatory treponemal tests suggested recent seroconversion. Given the re-emergence of congenital syphilis, our report aims to demonstrate the importance of rescreening women at increased risk and improve awareness of common manifestations of the syphilis disease in the newborn. For women at increased risk, repeat syphilis testing early in the third trimester and again at delivery in communities and populations with a high prevalence of syphilis is recommended | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a CDC, Centers for Disease Control and Prevention | |
| 650 | 4 | |a CSF, cerebrospinal fluid | |
| 650 | 4 | |a Condyloma lata | |
| 650 | 4 | |a Congenital syphilis | |
| 650 | 4 | |a Delivery | |
| 650 | 4 | |a HIV, Human Immunodeficiency Virus | |
| 650 | 4 | |a HSV, Herpes Simplex Virus | |
| 650 | 4 | |a PCR, Polymerase Chain Reaction | |
| 650 | 4 | |a Pregnancy | |
| 650 | 4 | |a RPR, Rapid Plasma Reagin | |
| 650 | 4 | |a Rescreening | |
| 650 | 4 | |a Reverse-sequence screening | |
| 650 | 4 | |a STIs, sexually transmitted infections | |
| 650 | 4 | |a VDRL, Venereal Disease Research Laboratory | |
| 700 | 1 | |a Gonzalez, Blanca E |e verfasserin |4 aut | |
| 700 | 1 | |a Esper, Frank P |e verfasserin |4 aut | |
| 700 | 1 | |a Tamburro, Joan |e verfasserin |4 aut | |
| 700 | 1 | |a Kadkhoda, Kamran |e verfasserin |4 aut | |
| 700 | 1 | |a Foster, Charles B |e verfasserin |4 aut | |
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