Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic

Copyright © 2020 Elsevier Ltd. All rights reserved..

INTRODUCTION: The world is facing the COVID-19 pandemic. The development of a vaccine is challenging. We aimed to determine the proportion of people who intend to get vaccinated against COVID-19 in France or to participate in a vaccine clinical trial.

METHODS: We conducted an anonymous on-line survey from the 26th of March to the 20th of April 2020. Primary endpoints were the intention to get vaccinated against COVID-19 if a vaccine was available or participate in a vaccine clinical trial.

RESULTS: Three thousand two hundred and fifty nine individuals answered the survey; women accounted for 67.4% of the respondents. According to their statements, 2.512 participants (77.6%, 95% CI 76.2-79%) will certainly or probably agree to get vaccinated against COVID-19. Older age, male gender, fear about COVID-19, being a healthcare worker and individual perceived risk were associated with COVID-19 vaccine acceptance. Vaccine hesitancy was associated with a decrease in COVID-19 vaccine acceptance. One thousand and five hundred and fifty respondents (47.6% 95% CI 45.9-49.3%) will certainly or probably agree to participate in a COVID-19 vaccine clinical trial. Older age, male gender, being a healthcare worker and individual perceived risk were associated with potential acceptance to participate in a COVID-19 vaccine clinical trial. Vaccine hesitancy was associated with refusal for participation in a COVID-19 vaccine clinical trial.

CONCLUSIONS: Nearly 75% and 48% of the survey respondents were respectively likely to accept vaccination or participation in a clinical trial against COVID-19. Vaccine hesitancy will be the major barrier to COVID-19 vaccine uptake.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:38

Enthalten in:

Vaccine - 38(2020), 45 vom: 21. Okt., Seite 7002-7006

Sprache:

Englisch

Beteiligte Personen:

Detoc, Maëlle [VerfasserIn]
Bruel, Sébastien [VerfasserIn]
Frappe, Paul [VerfasserIn]
Tardy, Bernard [VerfasserIn]
Botelho-Nevers, Elisabeth [VerfasserIn]
Gagneux-Brunon, Amandine [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
COVID-19 Vaccines
Journal Article
Pandemics
SARS-CoV-2
Vaccine
Vaccine hesitancy
Viral Vaccines

Anmerkungen:

Date Completed 22.10.2020

Date Revised 21.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.vaccine.2020.09.041

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM315593725