COVID-19 and sickle cell disease in Bahrain

Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved..

INTRODUCTION: Coronavirus disease 2019 (COVID-19) is caused by a newly identified strain of the coronavirus family that has been shown to affect the hemoglobin beta chain, the same chain that has sickle cell disease (SCD) mutation. This study was undertaken to see if COVID-19 infection increased disease severity in patients with SCD.

METHODS: Mass screening of the Bahraini population was undertaken between February and April 2020.

RESULTS: A total of 38,092 Bahraini people were tested for COVID-19 during this period; 378 (1%) were SCD patients. Six patients with SCD had COVID-19 (1.6%): three remained asymptomatic, two had mild symptoms and one required oxygen therapy. The SCD patients had a similar average length of stay when compared with non-SCD COVID-19 patients (10.7 days).

CONCLUSION: The infection rate, clinical course and viral clearance seen for the SCD patients with COVID-19 were no different to those without SCD.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:101

Enthalten in:

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 101(2020) vom: 20. Dez., Seite 14-16

Sprache:

Englisch

Beteiligte Personen:

AbdulRahman, Abdulkarim [VerfasserIn]
AlAli, Salman [VerfasserIn]
Yaghi, Omar [VerfasserIn]
Shabaan, Mohammed [VerfasserIn]
Otoom, Sameer [VerfasserIn]
Atkin, Stephen L [VerfasserIn]
AlQahtani, Manaf [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Journal Article
SARS-CoV-2
Sickle cell disease

Anmerkungen:

Date Completed 31.12.2020

Date Revised 18.05.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.ijid.2020.09.1433

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM315512768