Cooperation and Cheating among Germinating Spores
Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved..
Many microbes produce stress-resistant spores to survive unfavorable conditions [1-4] and enhance dispersal [1, 5]. Cooperative behavior is integral to the process of spore formation in some species [3, 6], but the degree to which germination of spore populations involves social interactions remains little explored. Myxococcus xanthus is a predatory soil bacterium that upon starvation forms spore-filled multicellular fruiting bodies that often harbor substantial diversity of endemic origin [7, 8]. Here we demonstrate that germination of M. xanthus spores formed during fruiting-body development is a social process involving at least two functionally distinct social molecules. Using pairs of natural isolates each derived from a single fruiting body that emerged on soil, we first show that spore germination exhibits positive density dependence due to a secreted "public-good" germination factor. Further, we find that a germination defect of one strain under saline stress in pure culture is complemented by addition of another strain that germinates well in saline environments and mediates cheating by the defective strain. Glycine betaine, an osmo-protectant utilized in all domains of life, is found to mediate saline-specific density dependence and cheating. Density dependence in non-saline conditions is mediated by a distinct factor, revealing socially complex spore germination involving multiple social molecules.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2020 |
---|---|
Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
---|---|
Enthalten in: |
Current biology : CB - 30(2020), 23 vom: 07. Dez., Seite 4745-4752.e4 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Pande, Samay [VerfasserIn] |
---|
Links: |
---|
Themen: |
3SCV180C9W |
---|
Anmerkungen: |
Date Completed 23.08.2021 Date Revised 23.08.2021 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1016/j.cub.2020.08.091 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM315475692 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM315475692 | ||
003 | DE-627 | ||
005 | 20231225155009.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2020 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1016/j.cub.2020.08.091 |2 doi | |
028 | 5 | 2 | |a pubmed24n1051.xml |
035 | |a (DE-627)NLM315475692 | ||
035 | |a (NLM)32976811 | ||
035 | |a (PII)S0960-9822(20)31281-1 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Pande, Samay |e verfasserin |4 aut | |
245 | 1 | 0 | |a Cooperation and Cheating among Germinating Spores |
264 | 1 | |c 2020 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 23.08.2021 | ||
500 | |a Date Revised 23.08.2021 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved. | ||
520 | |a Many microbes produce stress-resistant spores to survive unfavorable conditions [1-4] and enhance dispersal [1, 5]. Cooperative behavior is integral to the process of spore formation in some species [3, 6], but the degree to which germination of spore populations involves social interactions remains little explored. Myxococcus xanthus is a predatory soil bacterium that upon starvation forms spore-filled multicellular fruiting bodies that often harbor substantial diversity of endemic origin [7, 8]. Here we demonstrate that germination of M. xanthus spores formed during fruiting-body development is a social process involving at least two functionally distinct social molecules. Using pairs of natural isolates each derived from a single fruiting body that emerged on soil, we first show that spore germination exhibits positive density dependence due to a secreted "public-good" germination factor. Further, we find that a germination defect of one strain under saline stress in pure culture is complemented by addition of another strain that germinates well in saline environments and mediates cheating by the defective strain. Glycine betaine, an osmo-protectant utilized in all domains of life, is found to mediate saline-specific density dependence and cheating. Density dependence in non-saline conditions is mediated by a distinct factor, revealing socially complex spore germination involving multiple social molecules | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
650 | 4 | |a density dependence | |
650 | 4 | |a glycine betaine | |
650 | 4 | |a myxobacteria | |
650 | 4 | |a osmotic stress | |
650 | 4 | |a public goods | |
650 | 4 | |a social evolution | |
650 | 4 | |a spore germination | |
650 | 7 | |a Betaine |2 NLM | |
650 | 7 | |a 3SCV180C9W |2 NLM | |
700 | 1 | |a Pérez Escriva, Pau |e verfasserin |4 aut | |
700 | 1 | |a Yu, Yuen-Tsu Nicco |e verfasserin |4 aut | |
700 | 1 | |a Sauer, Uwe |e verfasserin |4 aut | |
700 | 1 | |a Velicer, Gregory J |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Current biology : CB |d 1991 |g 30(2020), 23 vom: 07. Dez., Seite 4745-4752.e4 |w (DE-627)NLM074990292 |x 1879-0445 |7 nnns |
773 | 1 | 8 | |g volume:30 |g year:2020 |g number:23 |g day:07 |g month:12 |g pages:4745-4752.e4 |
856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.cub.2020.08.091 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 30 |j 2020 |e 23 |b 07 |c 12 |h 4745-4752.e4 |