COVID-19 Neurological Manifestations and Underlying Mechanisms : A Scoping Review
Copyright © 2020 Wenting, Gruters, van Os, Verstraeten, Valentijn, Ponds and de Vugt..
BACKGROUND: In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement and cognitive consequences.
METHODS: A scoping review was conducted with multiple searches in PubMed, PsycInfo, and CINAHL databases. Full text articles in English were included if they involved humans with COVID-19. The search was updated twice, the latest on 19 May 2020.
RESULTS: After screening 266 records and cross referencing, 85 articles were included. The articles were case studies, opinion papers, letters to editors, and a few observational studies. No articles were found regarding cognitive consequences in COVID-19 patients. All reported on neurological manifestations and/or underlying mechanisms of CNS involvement in COVID-19.
CONCLUSION: Neurological manifestations of COVID-19 vary from mild (e.g. loss of taste and smell, dizziness, headache) to severe (e.g. ischemic stroke, encephalitis). Underlying pathways are suggested to be both indirect (as a result of thrombotic complication, inflammatory consequences, hypoxia, blood pressure dysregulation), and direct (neurotropic properties of the virus). Since most articles were opinion papers and no studies have been conducted on cognitive consequences, further research is warranted.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2020 |
---|---|
Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
---|---|
Enthalten in: |
Frontiers in psychiatry - 11(2020) vom: 24., Seite 860 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Wenting, Angela [VerfasserIn] |
---|
Links: |
---|
Themen: |
Cognitive |
---|
Anmerkungen: |
Date Revised 17.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
---|
doi: |
10.3389/fpsyt.2020.00860 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM315443782 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM315443782 | ||
003 | DE-627 | ||
005 | 20231225154928.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2020 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3389/fpsyt.2020.00860 |2 doi | |
028 | 5 | 2 | |a pubmed24n1051.xml |
035 | |a (DE-627)NLM315443782 | ||
035 | |a (NLM)32973590 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Wenting, Angela |e verfasserin |4 aut | |
245 | 1 | 0 | |a COVID-19 Neurological Manifestations and Underlying Mechanisms |b A Scoping Review |
264 | 1 | |c 2020 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 17.04.2022 | ||
500 | |a published: Electronic-eCollection | ||
500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a Copyright © 2020 Wenting, Gruters, van Os, Verstraeten, Valentijn, Ponds and de Vugt. | ||
520 | |a BACKGROUND: In the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement and cognitive consequences | ||
520 | |a METHODS: A scoping review was conducted with multiple searches in PubMed, PsycInfo, and CINAHL databases. Full text articles in English were included if they involved humans with COVID-19. The search was updated twice, the latest on 19 May 2020 | ||
520 | |a RESULTS: After screening 266 records and cross referencing, 85 articles were included. The articles were case studies, opinion papers, letters to editors, and a few observational studies. No articles were found regarding cognitive consequences in COVID-19 patients. All reported on neurological manifestations and/or underlying mechanisms of CNS involvement in COVID-19 | ||
520 | |a CONCLUSION: Neurological manifestations of COVID-19 vary from mild (e.g. loss of taste and smell, dizziness, headache) to severe (e.g. ischemic stroke, encephalitis). Underlying pathways are suggested to be both indirect (as a result of thrombotic complication, inflammatory consequences, hypoxia, blood pressure dysregulation), and direct (neurotropic properties of the virus). Since most articles were opinion papers and no studies have been conducted on cognitive consequences, further research is warranted | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Review | |
650 | 4 | |a Corona Virus Disease 2019 | |
650 | 4 | |a cognitive | |
650 | 4 | |a neurological | |
650 | 4 | |a neurotropic | |
650 | 4 | |a scoping review | |
700 | 1 | |a Gruters, Angélique |e verfasserin |4 aut | |
700 | 1 | |a van Os, Yindee |e verfasserin |4 aut | |
700 | 1 | |a Verstraeten, Sonja |e verfasserin |4 aut | |
700 | 1 | |a Valentijn, Susanne |e verfasserin |4 aut | |
700 | 1 | |a Ponds, Rudolf |e verfasserin |4 aut | |
700 | 1 | |a de Vugt, Marjolein |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Frontiers in psychiatry |d 2010 |g 11(2020) vom: 24., Seite 860 |w (DE-627)NLM205737781 |x 1664-0640 |7 nnns |
773 | 1 | 8 | |g volume:11 |g year:2020 |g day:24 |g pages:860 |
856 | 4 | 0 | |u http://dx.doi.org/10.3389/fpsyt.2020.00860 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 11 |j 2020 |b 24 |h 860 |