Animal models for COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in 2019 (first detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread to 215 countries, has infected more than 30 million people and has caused more than 950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there is an urgent need to develop therapeutic agents and vaccines to mitigate the current pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World Health Organization (WHO) assembled an international panel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agents. Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19.
| Errataetall: |
CommentIn: Respirology. 2021 Mar;26(3):222-224. - PMID 33350019 |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:586 |
|---|---|
| Enthalten in: |
Nature - 586(2020), 7830 vom: 01. Okt., Seite 509-515 |
| Sprache: |
Englisch |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 29.10.2020 Date Revised 11.11.2023 published: Print-Electronic CommentIn: Respirology. 2021 Mar;26(3):222-224. - PMID 33350019 Citation Status MEDLINE |
|---|
| doi: |
10.1038/s41586-020-2787-6 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM315378999 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM315378999 | ||
| 003 | DE-627 | ||
| 005 | 20231225154804.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/s41586-020-2787-6 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1051.xml |
| 035 | |a (DE-627)NLM315378999 | ||
| 035 | |a (NLM)32967005 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Muñoz-Fontela, César |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Animal models for COVID-19 |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 29.10.2020 | ||
| 500 | |a Date Revised 11.11.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: Respirology. 2021 Mar;26(3):222-224. - PMID 33350019 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in 2019 (first detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread to 215 countries, has infected more than 30 million people and has caused more than 950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there is an urgent need to develop therapeutic agents and vaccines to mitigate the current pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World Health Organization (WHO) assembled an international panel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agents. Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a COVID-19 Vaccines |2 NLM | |
| 650 | 7 | |a Viral Vaccines |2 NLM | |
| 700 | 1 | |a Dowling, William E |e verfasserin |4 aut | |
| 700 | 1 | |a Funnell, Simon G P |e verfasserin |4 aut | |
| 700 | 1 | |a Gsell, Pierre-S |e verfasserin |4 aut | |
| 700 | 1 | |a Riveros-Balta, A Ximena |e verfasserin |4 aut | |
| 700 | 1 | |a Albrecht, Randy A |e verfasserin |4 aut | |
| 700 | 1 | |a Andersen, Hanne |e verfasserin |4 aut | |
| 700 | 1 | |a Baric, Ralph S |e verfasserin |4 aut | |
| 700 | 1 | |a Carroll, Miles W |e verfasserin |4 aut | |
| 700 | 1 | |a Cavaleri, Marco |e verfasserin |4 aut | |
| 700 | 1 | |a Qin, Chuan |e verfasserin |4 aut | |
| 700 | 1 | |a Crozier, Ian |e verfasserin |4 aut | |
| 700 | 1 | |a Dallmeier, Kai |e verfasserin |4 aut | |
| 700 | 1 | |a de Waal, Leon |e verfasserin |4 aut | |
| 700 | 1 | |a de Wit, Emmie |e verfasserin |4 aut | |
| 700 | 1 | |a Delang, Leen |e verfasserin |4 aut | |
| 700 | 1 | |a Dohm, Erik |e verfasserin |4 aut | |
| 700 | 1 | |a Duprex, W Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Falzarano, Darryl |e verfasserin |4 aut | |
| 700 | 1 | |a Finch, Courtney L |e verfasserin |4 aut | |
| 700 | 1 | |a Frieman, Matthew B |e verfasserin |4 aut | |
| 700 | 1 | |a Graham, Barney S |e verfasserin |4 aut | |
| 700 | 1 | |a Gralinski, Lisa E |e verfasserin |4 aut | |
| 700 | 1 | |a Guilfoyle, Kate |e verfasserin |4 aut | |
| 700 | 1 | |a Haagmans, Bart L |e verfasserin |4 aut | |
| 700 | 1 | |a Hamilton, Geraldine A |e verfasserin |4 aut | |
| 700 | 1 | |a Hartman, Amy L |e verfasserin |4 aut | |
| 700 | 1 | |a Herfst, Sander |e verfasserin |4 aut | |
| 700 | 1 | |a Kaptein, Suzanne J F |e verfasserin |4 aut | |
| 700 | 1 | |a Klimstra, William B |e verfasserin |4 aut | |
| 700 | 1 | |a Knezevic, Ivana |e verfasserin |4 aut | |
| 700 | 1 | |a Krause, Philip R |e verfasserin |4 aut | |
| 700 | 1 | |a Kuhn, Jens H |e verfasserin |4 aut | |
| 700 | 1 | |a Le Grand, Roger |e verfasserin |4 aut | |
| 700 | 1 | |a Lewis, Mark G |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Wen-Chun |e verfasserin |4 aut | |
| 700 | 1 | |a Maisonnasse, Pauline |e verfasserin |4 aut | |
| 700 | 1 | |a McElroy, Anita K |e verfasserin |4 aut | |
| 700 | 1 | |a Munster, Vincent |e verfasserin |4 aut | |
| 700 | 1 | |a Oreshkova, Nadia |e verfasserin |4 aut | |
| 700 | 1 | |a Rasmussen, Angela L |e verfasserin |4 aut | |
| 700 | 1 | |a Rocha-Pereira, Joana |e verfasserin |4 aut | |
| 700 | 1 | |a Rockx, Barry |e verfasserin |4 aut | |
| 700 | 1 | |a Rodríguez, Estefanía |e verfasserin |4 aut | |
| 700 | 1 | |a Rogers, Thomas F |e verfasserin |4 aut | |
| 700 | 1 | |a Salguero, Francisco J |e verfasserin |4 aut | |
| 700 | 1 | |a Schotsaert, Michael |e verfasserin |4 aut | |
| 700 | 1 | |a Stittelaar, Koert J |e verfasserin |4 aut | |
| 700 | 1 | |a Thibaut, Hendrik Jan |e verfasserin |4 aut | |
| 700 | 1 | |a Tseng, Chien-Te |e verfasserin |4 aut | |
| 700 | 1 | |a Vergara-Alert, Júlia |e verfasserin |4 aut | |
| 700 | 1 | |a Beer, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Brasel, Trevor |e verfasserin |4 aut | |
| 700 | 1 | |a Chan, Jasper F W |e verfasserin |4 aut | |
| 700 | 1 | |a García-Sastre, Adolfo |e verfasserin |4 aut | |
| 700 | 1 | |a Neyts, Johan |e verfasserin |4 aut | |
| 700 | 1 | |a Perlman, Stanley |e verfasserin |4 aut | |
| 700 | 1 | |a Reed, Douglas S |e verfasserin |4 aut | |
| 700 | 1 | |a Richt, Juergen A |e verfasserin |4 aut | |
| 700 | 1 | |a Roy, Chad J |e verfasserin |4 aut | |
| 700 | 1 | |a Segalés, Joaquim |e verfasserin |4 aut | |
| 700 | 1 | |a Vasan, Seshadri S |e verfasserin |4 aut | |
| 700 | 1 | |a Henao-Restrepo, Ana María |e verfasserin |4 aut | |
| 700 | 1 | |a Barouch, Dan H |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature |d 1945 |g 586(2020), 7830 vom: 01. Okt., Seite 509-515 |w (DE-627)NLM000008257 |x 1476-4687 |7 nnns |
| 773 | 1 | 8 | |g volume:586 |g year:2020 |g number:7830 |g day:01 |g month:10 |g pages:509-515 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1038/s41586-020-2787-6 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 586 |j 2020 |e 7830 |b 01 |c 10 |h 509-515 | ||