Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA
© The Author(s) 2020..
BACKGROUND: Novel coronavirus 2019 (COVID-19) has been the focus of the medical world since being declared a pandemic in March 2020. While the pathogenesis and heterogeneity of COVID-19 manifestations is still not fully understood, viral evasion of cellular immune responses and inflammatory dysregulation are believed to play essential roles in disease progression and severity.
CASE PRESENTATION: We present the first case of a patient with COVID-19 with massive pulmonary embolism treated successfully with systemic thrombolysis, VA-ECLS, and bail out catheter directed thrombolysis. He was discharged from the hospital after an eventful hospital course on therapeutic anticoagulation with warfarin.
CONCLUSIONS: We present the first case of a patient with COVID-19 with massive pulmonary embolism (PE) treated successfully with systemic thrombolysis, VA-ECLS and bail out catheter directed thrombolysis. In our experience catheter directed thrombolysis comes with an acceptable bleeding risk despite use of mechanical circulatory support, particularly with meticulous attention to vascular access and dose response monitoring.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
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| Enthalten in: |
Clinical medicine insights. Circulatory, respiratory and pulmonary medicine - 14(2020) vom: 20., Seite 1179548420957451 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Akoluk, Arda [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Revised 17.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1177/1179548420957451 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM315237465 |
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| 245 | 1 | 0 | |a Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA |
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| 500 | |a Date Revised 17.04.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © The Author(s) 2020. | ||
| 520 | |a BACKGROUND: Novel coronavirus 2019 (COVID-19) has been the focus of the medical world since being declared a pandemic in March 2020. While the pathogenesis and heterogeneity of COVID-19 manifestations is still not fully understood, viral evasion of cellular immune responses and inflammatory dysregulation are believed to play essential roles in disease progression and severity | ||
| 520 | |a CASE PRESENTATION: We present the first case of a patient with COVID-19 with massive pulmonary embolism treated successfully with systemic thrombolysis, VA-ECLS, and bail out catheter directed thrombolysis. He was discharged from the hospital after an eventful hospital course on therapeutic anticoagulation with warfarin | ||
| 520 | |a CONCLUSIONS: We present the first case of a patient with COVID-19 with massive pulmonary embolism (PE) treated successfully with systemic thrombolysis, VA-ECLS and bail out catheter directed thrombolysis. In our experience catheter directed thrombolysis comes with an acceptable bleeding risk despite use of mechanical circulatory support, particularly with meticulous attention to vascular access and dose response monitoring | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a VA-ECMO | |
| 650 | 4 | |a pulmonary embolism | |
| 650 | 4 | |a tPA | |
| 650 | 4 | |a thrombolysis | |
| 700 | 1 | |a Mazahir, Usman |e verfasserin |4 aut | |
| 700 | 1 | |a Douedi, Steven |e verfasserin |4 aut | |
| 700 | 1 | |a Aziz, Adel |e verfasserin |4 aut | |
| 700 | 1 | |a Obagi, Aref |e verfasserin |4 aut | |
| 700 | 1 | |a Kiss, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Flynn, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Costanzo, Eric |e verfasserin |4 aut | |
| 700 | 1 | |a Simsir, Sinan A |e verfasserin |4 aut | |
| 700 | 1 | |a Saybolt, Matthew D |e verfasserin |4 aut | |
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