Convalescent plasma as a treatment modality for coronavirus disease 2019 in Sudan

Copyright © 2020 Elsevier Ltd. All rights reserved..

Coronavirus disease 2019 (COVID-19) is a disease spreading rapidly in Sudan, the rest of the African continent and the world with no known definitive treatment or vaccines. However, among many treatment interventions being tested globally, beneficial effects and clinical improvements have been reported when convalescent plasma is used for treating COVID-19 patients. We prepared a guiding protocol for treating early to moderate COVID-19 patients with plasma transfusion from convalescent COVID-19 patients. This protocol was deduced based on previously published reports and studies that evaluated and tested convalescent plasma as a prospective therapy for COVID-19 patients. The protocol covers instructions on patient and donor selection criteria, plasma harvesting, plasma product specifications, dosage and precautions for convalescent plasma collection and transfusion process. Altogether, we prepared a treatment protocol that is tailored to the context of Sudan to be adopted by Sudan's health authority. Moreover, it will also provide reference for researchers to design open label clinical trials for convalescent plasma transfusion.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:59

Enthalten in:

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis - 59(2020), 6 vom: 30. Dez., Seite 102918

Sprache:

Englisch

Beteiligte Personen:

Hassan, Mozan Osman [VerfasserIn]
Osman, Asma Ahmed [VerfasserIn]
Elbasit, Hana Elsir Abd [VerfasserIn]
Hassan, Hanan Elsamani [VerfasserIn]
Rufai, Hala [VerfasserIn]
Satti, Maria M M [VerfasserIn]
Elnegoumi, Musab [VerfasserIn]
Idris, Roaa [VerfasserIn]
Musa, Ashraf [VerfasserIn]
Ali, Abdelhakam H [VerfasserIn]
Zroog, Susan Ali [VerfasserIn]
Altayb, Abduelbagi D A [VerfasserIn]
Khairy, Amna [VerfasserIn]
Allam, Mushal [VerfasserIn]
Abdelhalim, Asaad Tageldein Idris [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Convalescent plasma
Journal Article
Protocol
SARS-CoV-2
Treatment

Anmerkungen:

Date Completed 21.12.2020

Date Revised 12.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.transci.2020.102918

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM31473242X