Clinical impact of early reinsertion of a central venous catheter after catheter removal in patients with catheter-related bloodstream infections
OBJECTIVE: Early replacement of a new central venous catheter (CVC) may pose a risk of persistent or recurrent infection in patients with a catheter-related bloodstream infection (CRBSI). We evaluated the clinical impact of early CVC reinsertion after catheter removal in patients with CRBSIs.
METHODS: We conducted a retrospective chart review of adult patients with confirmed CRBSIs in 2 tertiary-care hospitals over a 7-year period.
RESULTS: To treat their infections, 316 patients with CRBSIs underwent CVC removal. Among them, 130 (41.1%) underwent early CVC reinsertion (≤3 days after CVC removal), 39 (12.4%) underwent delayed reinsertion (>3 days), and 147 (46.5%) did not undergo CVC reinsertion. There were no differences in baseline characteristics among the 3 groups, except for nontunneled CVC, presence of septic shock, and reason for CVC reinsertion. The rate of persistent CRBSI in the early CVC reinsertion group (22.3%) was higher than that in the no CVC reinsertion group (7.5%; P = .002) but was similar to that in the delayed CVC reinsertion group (17.9%; P > .99). The other clinical outcomes did not differ among the 3 groups, including rates of 30-day mortality, complicated infection, and recurrence. After controlling for several confounding factors, early CVC reinsertion was not significantly associated with persistent CRBSI (OR, 1.59; P = .35) or 30-day mortality compared with delayed CVC reinsertion (OR, 0.81; P = .68).
CONCLUSIONS: Early CVC reinsertion in the setting of CRBSI may be safe. Replacement of a new CVC should not be delayed in patients who still require a CVC for ongoing management.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
|---|---|
| Enthalten in: |
Infection control and hospital epidemiology - 42(2021), 2 vom: 08. Feb., Seite 162-168 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Lee, Yu-Mi [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 31.08.2021 Date Revised 31.08.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1017/ice.2020.405 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM314730516 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM314730516 | ||
| 003 | DE-627 | ||
| 005 | 20231225153353.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1017/ice.2020.405 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1049.xml |
| 035 | |a (DE-627)NLM314730516 | ||
| 035 | |a (NLM)32900398 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Lee, Yu-Mi |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical impact of early reinsertion of a central venous catheter after catheter removal in patients with catheter-related bloodstream infections |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 31.08.2021 | ||
| 500 | |a Date Revised 31.08.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: Early replacement of a new central venous catheter (CVC) may pose a risk of persistent or recurrent infection in patients with a catheter-related bloodstream infection (CRBSI). We evaluated the clinical impact of early CVC reinsertion after catheter removal in patients with CRBSIs | ||
| 520 | |a METHODS: We conducted a retrospective chart review of adult patients with confirmed CRBSIs in 2 tertiary-care hospitals over a 7-year period | ||
| 520 | |a RESULTS: To treat their infections, 316 patients with CRBSIs underwent CVC removal. Among them, 130 (41.1%) underwent early CVC reinsertion (≤3 days after CVC removal), 39 (12.4%) underwent delayed reinsertion (>3 days), and 147 (46.5%) did not undergo CVC reinsertion. There were no differences in baseline characteristics among the 3 groups, except for nontunneled CVC, presence of septic shock, and reason for CVC reinsertion. The rate of persistent CRBSI in the early CVC reinsertion group (22.3%) was higher than that in the no CVC reinsertion group (7.5%; P = .002) but was similar to that in the delayed CVC reinsertion group (17.9%; P > .99). The other clinical outcomes did not differ among the 3 groups, including rates of 30-day mortality, complicated infection, and recurrence. After controlling for several confounding factors, early CVC reinsertion was not significantly associated with persistent CRBSI (OR, 1.59; P = .35) or 30-day mortality compared with delayed CVC reinsertion (OR, 0.81; P = .68) | ||
| 520 | |a CONCLUSIONS: Early CVC reinsertion in the setting of CRBSI may be safe. Replacement of a new CVC should not be delayed in patients who still require a CVC for ongoing management | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a Ryu, Byung-Han |e verfasserin |4 aut | |
| 700 | 1 | |a Hong, Sun In |e verfasserin |4 aut | |
| 700 | 1 | |a Cho, Oh-Hyun |e verfasserin |4 aut | |
| 700 | 1 | |a Hong, Kyung-Wook |e verfasserin |4 aut | |
| 700 | 1 | |a Bae, In-Gyu |e verfasserin |4 aut | |
| 700 | 1 | |a Kwack, Won Gun |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Young Jin |e verfasserin |4 aut | |
| 700 | 1 | |a Chung, Eun Kyoung |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Dong Youn |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Mi Suk |e verfasserin |4 aut | |
| 700 | 1 | |a Park, Ki-Ho |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Infection control and hospital epidemiology |d 1988 |g 42(2021), 2 vom: 08. Feb., Seite 162-168 |w (DE-627)NLM012701467 |x 1559-6834 |7 nnns |
| 773 | 1 | 8 | |g volume:42 |g year:2021 |g number:2 |g day:08 |g month:02 |g pages:162-168 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1017/ice.2020.405 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 42 |j 2021 |e 2 |b 08 |c 02 |h 162-168 | ||