How can nanotechnology help to combat COVID-19? Opportunities and urgent need

Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R0 values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Journal of nanobiotechnology - 18(2020), 1 vom: 05. Sept., Seite 125

Sprache:

Englisch

Beteiligte Personen:

Campos, Estefânia V R [VerfasserIn]
Pereira, Anderson E S [VerfasserIn]
de Oliveira, Jhones Luiz [VerfasserIn]
Carvalho, Lucas Bragança [VerfasserIn]
Guilger-Casagrande, Mariana [VerfasserIn]
de Lima, Renata [VerfasserIn]
Fraceto, Leonardo Fernandes [VerfasserIn]

Links:

Volltext

Themen:

Antiviral Agents
COVID-19 Vaccines
Coronavirus
Drug Carriers
Journal Article
Nano-vaccines
Nanoparticles
Nanosensors
Nanotechnology
Review
SARS-CoV-2
Viral Vaccines

Anmerkungen:

Date Completed 10.09.2020

Date Revised 04.11.2023

published: Electronic

Citation Status MEDLINE

doi:

10.1186/s12951-020-00685-4

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM31463889X