Alveolar proteinosis due to toxic inhalation at workplace
© 2020 The Authors..
We report a clinical case of a 39-year old male, without any known previous medical condition but with occupational exposure to paints and dust cement, who presented an autoimmune pulmonary alveolar proteinosis (PAP) triggered by exposure to toxic inhalation at his workplace. PAP is a rare lung disease characterized by intra-alveolar abnormal accumulation of surfactant. The presence of a crazy-paving pattern in high-resolution computed tomography scan brings the suspicion of PAP although histopathology results of bronchoalveolar lavage are always required for its final diagnosis. The autoimmune form of PAP due to toxic inhalation, such as the one here described, is rare and it is usually difficult to establish a causal relationship.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
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| Enthalten in: |
Respiratory medicine case reports - 31(2020) vom: 01., Seite 101199 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Santos, Gabriela F [VerfasserIn] |
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| Links: |
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| Themen: |
Alveolar proteinosis |
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| Anmerkungen: |
Date Revised 17.12.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.rmcr.2020.101199 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM314420533 |
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| 520 | |a © 2020 The Authors. | ||
| 520 | |a We report a clinical case of a 39-year old male, without any known previous medical condition but with occupational exposure to paints and dust cement, who presented an autoimmune pulmonary alveolar proteinosis (PAP) triggered by exposure to toxic inhalation at his workplace. PAP is a rare lung disease characterized by intra-alveolar abnormal accumulation of surfactant. The presence of a crazy-paving pattern in high-resolution computed tomography scan brings the suspicion of PAP although histopathology results of bronchoalveolar lavage are always required for its final diagnosis. The autoimmune form of PAP due to toxic inhalation, such as the one here described, is rare and it is usually difficult to establish a causal relationship | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Alveolar proteinosis | |
| 650 | 4 | |a Autoimmunity | |
| 650 | 4 | |a Hypoxemia | |
| 650 | 4 | |a Rare lung disease | |
| 650 | 4 | |a Toxic inhalation | |
| 700 | 1 | |a Portela, João |e verfasserin |4 aut | |
| 700 | 1 | |a Argyropoulou, Despoina |e verfasserin |4 aut | |
| 700 | 1 | |a Varudo, Rita |e verfasserin |4 aut | |
| 700 | 1 | |a Pimenta, Inês |e verfasserin |4 aut | |
| 700 | 1 | |a Oliveira, Ana |e verfasserin |4 aut | |
| 700 | 1 | |a Lança, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Fernandes, Antero |e verfasserin |4 aut | |
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