Re-positive coronavirus disease 2019 PCR test : could it be a reinfection?
© 2020 The Authors..
The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight RT-qPCR positivity re-detection after discharge from isolation, with special consideration of the possible reasons behind it. We found that re-positive RT-qPCR assays for severe acute respiratory syndrome coronavirus 2 after previous negative results might be attributed to false-negative laboratory results and prolonged viral shedding, rather than to re-infection. These findings are encouraging and should be validated in a larger cohort.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:37 |
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Enthalten in: |
New microbes and new infections - 37(2020) vom: 26. Sept., Seite 100748 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Osman, A A [VerfasserIn] |
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Links: |
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Themen: |
CT scan |
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Anmerkungen: |
Date Revised 12.11.2023 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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doi: |
10.1016/j.nmni.2020.100748 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM314173293 |
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520 | |a The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight RT-qPCR positivity re-detection after discharge from isolation, with special consideration of the possible reasons behind it. We found that re-positive RT-qPCR assays for severe acute respiratory syndrome coronavirus 2 after previous negative results might be attributed to false-negative laboratory results and prolonged viral shedding, rather than to re-infection. These findings are encouraging and should be validated in a larger cohort | ||
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