In vivo characterization of the structures of films of a fatty acid and an alcohol adsorbed on the skin surface
Copyright © 2020 Elsevier B.V. All rights reserved..
An in vivo analysis of stearyl alcohol and stearic acid films on the skin surface using polarized infrared-external reflection spectroscopy revealed that whether the sample molecules adopt an energetically stable conformation and orientation strongly depends on the molecular functionalities and sample preparation conditions. For stearic acid, even the difference in solute concentration between 0.1 and 0.5 wt% results in a different molecular conformation and orientation. This illustrates that the molecular organization of the adsorbate on the skin surface is sensitively determined by the kinetics of the sample film growth, not by the simple thermodynamic equilibrium with the skin temperature.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:266 |
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| Enthalten in: |
Biophysical chemistry - 266(2020) vom: 01. Nov., Seite 106459 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hama, Tetsuya [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 14.06.2021 Date Revised 14.06.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.bpc.2020.106459 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 500 | |a Date Revised 14.06.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 Elsevier B.V. All rights reserved. | ||
| 520 | |a An in vivo analysis of stearyl alcohol and stearic acid films on the skin surface using polarized infrared-external reflection spectroscopy revealed that whether the sample molecules adopt an energetically stable conformation and orientation strongly depends on the molecular functionalities and sample preparation conditions. For stearic acid, even the difference in solute concentration between 0.1 and 0.5 wt% results in a different molecular conformation and orientation. This illustrates that the molecular organization of the adsorbate on the skin surface is sensitively determined by the kinetics of the sample film growth, not by the simple thermodynamic equilibrium with the skin temperature | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Epidermis | |
| 650 | 4 | |a External reflection spectrometry | |
| 650 | 4 | |a Human skin | |
| 650 | 4 | |a Infrared spectroscopy | |
| 650 | 4 | |a Molecular organization | |
| 650 | 4 | |a Surface selection rules | |
| 650 | 7 | |a Fatty Alcohols |2 NLM | |
| 650 | 7 | |a Stearic Acids |2 NLM | |
| 650 | 7 | |a stearyl alcohol |2 NLM | |
| 650 | 7 | |a 2KR89I4H1Y |2 NLM | |
| 650 | 7 | |a stearic acid |2 NLM | |
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| 700 | 1 | |a Kouchi, Akira |e verfasserin |4 aut | |
| 700 | 1 | |a Watanabe, Naoki |e verfasserin |4 aut | |
| 700 | 1 | |a Shioya, Nobutaka |e verfasserin |4 aut | |
| 700 | 1 | |a Shimoaka, Takafumi |e verfasserin |4 aut | |
| 700 | 1 | |a Hasegawa, Takeshi |e verfasserin |4 aut | |
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