Self-reported course of olfactory impairment determines outcome for successful surgical intervention in nasal polyps with anosmia
BACKGROUND: Olfactory impairment is one of important symptoms of Chronic rhinosinusitis with nasal polyps (CRSwNP). However, the relationship between course of olfactory impairment and postoperative symptom improvement was still unclear.
OBJECTIVE: The aim of this study was to assess the relationship between the self-reported course of olfactory loss and the degree of improvement in olfaction to determine the timing for successful surgical intervention in improving olfaction in patients with CRSwNP.
MATERIALS AND METHODS: A total of 86 CRSwNP patients with loss of smell and undergoing functional endoscopic sinus surgery (FESS) were recruited consecutively. The self-reported course of smell lose before treatment was recorded. Olfactory function was recorded before and after FESS using T&T Olfactometry.
RESULTS: Fifty-seven patients demonstrated recovery of olfaction and 29 patients no-recovery. The average recovery time of smell loss in the study was 2.6 weeks. The course of smell loss showed moderate accuracy as a marker for determining the timing for successful FESS; with up to 4.5 years of self-reported smell loss being the cut-off point for recovery of smell following FESS.
CONCLUSION: This study suggests that FESS in CRSwNP patients with self-reported significant olfactory impairment for less than 4.5 years may lead to improvement in olfaction.
SIGNIFICANCE: FESS in CRSwNP patients with self-reported significant olfactory impairment persisting for less than 4.5 years may lead to considerable improvement in olfaction in these patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:140 |
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| Enthalten in: |
Acta oto-laryngologica - 140(2020), 12 vom: 17. Dez., Seite 1021-1027 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhang, Wei [VerfasserIn] |
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| Links: |
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| Themen: |
Chronic rhinosinusitis |
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| Anmerkungen: |
Date Completed 10.09.2021 Date Revised 10.09.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/00016489.2020.1805508 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM31383380X |
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| 245 | 1 | 0 | |a Self-reported course of olfactory impairment determines outcome for successful surgical intervention in nasal polyps with anosmia |
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| 500 | |a Date Revised 10.09.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Olfactory impairment is one of important symptoms of Chronic rhinosinusitis with nasal polyps (CRSwNP). However, the relationship between course of olfactory impairment and postoperative symptom improvement was still unclear | ||
| 520 | |a OBJECTIVE: The aim of this study was to assess the relationship between the self-reported course of olfactory loss and the degree of improvement in olfaction to determine the timing for successful surgical intervention in improving olfaction in patients with CRSwNP | ||
| 520 | |a MATERIALS AND METHODS: A total of 86 CRSwNP patients with loss of smell and undergoing functional endoscopic sinus surgery (FESS) were recruited consecutively. The self-reported course of smell lose before treatment was recorded. Olfactory function was recorded before and after FESS using T&T Olfactometry | ||
| 520 | |a RESULTS: Fifty-seven patients demonstrated recovery of olfaction and 29 patients no-recovery. The average recovery time of smell loss in the study was 2.6 weeks. The course of smell loss showed moderate accuracy as a marker for determining the timing for successful FESS; with up to 4.5 years of self-reported smell loss being the cut-off point for recovery of smell following FESS | ||
| 520 | |a CONCLUSION: This study suggests that FESS in CRSwNP patients with self-reported significant olfactory impairment for less than 4.5 years may lead to improvement in olfaction | ||
| 520 | |a SIGNIFICANCE: FESS in CRSwNP patients with self-reported significant olfactory impairment persisting for less than 4.5 years may lead to considerable improvement in olfaction in these patients | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Chronic rhinosinusitis | |
| 650 | 4 | |a T&T olfactometry | |
| 650 | 4 | |a course of smell loss | |
| 650 | 4 | |a functional endoscopic sinus surgery | |
| 650 | 4 | |a predictive | |
| 650 | 4 | |a receiver operative curve | |
| 700 | 1 | |a Meng, Yifan |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Chengshuo |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Feifei |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Luo |e verfasserin |4 aut | |
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