Cerebrospinal Fluid Features in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive Patients
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com..
This study analyzed the cerebrospinal fluid features of 31 coronavirus disease 2019 (COVID-19) patients with neurological complications. We observed neither severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the cerebrospinal fluid, nor intrathecal immunoglobulin G (IgG) synthesis but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:73 |
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| Enthalten in: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 73(2021), 9 vom: 02. Nov., Seite e3102-e3105 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bellon, Mathilde [VerfasserIn] |
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| Links: |
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| Themen: |
Blood-brain barrier |
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| Anmerkungen: |
Date Completed 08.11.2021 Date Revised 08.11.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/cid/ciaa1165 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM31345213X |
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| 520 | |a © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com. | ||
| 520 | |a This study analyzed the cerebrospinal fluid features of 31 coronavirus disease 2019 (COVID-19) patients with neurological complications. We observed neither severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the cerebrospinal fluid, nor intrathecal immunoglobulin G (IgG) synthesis but did observe signs of blood-brain barrier disruption. These results might serve as a basis for a better understanding of SARS-CoV-2 related neuropathogenesis | ||
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| 700 | 1 | |a Cherpillod, Pascal |e verfasserin |4 aut | |
| 700 | 1 | |a Vazquez, Jessica |e verfasserin |4 aut | |
| 700 | 1 | |a Lalive, Patrice H |e verfasserin |4 aut | |
| 700 | 1 | |a Schibler, Manuel |e verfasserin |4 aut | |
| 700 | 1 | |a Deffert, Christine |e verfasserin |4 aut | |
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