Is COVID-19 Similar in Pregnant and Non-Pregnant Women?

Copyright © 2020, Selim et al..

Approximately one-third of infected pregnant women died from severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) epidemics of the past two decades. It is logical to predict that pregnant women infected with the novel coronavirus (SARS-CoV-2) might be at higher risk for severe illness, morbidity, or mortality compared with non-pregnant women. However, a review of the literature indicates that pregnant women are not more likely to be seriously ill than other healthy non-pregnant women if they develop coronavirus disease (COVID-19). This observation begs the question: "Why does pregnancy not increase the risk for acquiring SARS-CoV-2 infection, nor does it worsen the clinical course of COVID-19 compared with non-pregnant individuals?" Herein, we try to explain our observations when considering whether the immunologic changes of pregnancy and other physiologic adaptations of pregnancy affect the virulence and course of SARS-CoV-2 infection.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:12

Enthalten in:

Cureus - 12(2020), 6 vom: 28. Juni, Seite e8888

Sprache:

Englisch

Beteiligte Personen:

Selim, Mohamed [VerfasserIn]
Mohamed, Sherif [VerfasserIn]
Abdo, Manal [VerfasserIn]
Abdelhaffez, Azza [VerfasserIn]

Links:

Volltext

Themen:

Adaptive immunity
Ards
Better outcomes
Cell-mediated immunity
Clinical features
Complications’
Covid-19
Covid-19 in pregnancy
Human pathophysiology
Journal Article
Review

Anmerkungen:

Date Revised 28.09.2020

published: Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.7759/cureus.8888

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM313182132