A Novel Framework Using Remote Telesimulation With Standardized Parents to Improve Research Staff Preparedness for Informed Consent in Pediatric Critical Care Research
OBJECTIVES: The Heart And Lung Failure-Pediatric INsulin Titration study was experiencing poor subject enrollment due to low rates of informed consent. Heart And Lung Failure-Pediatric INsulin Titration investigators collaborated with the Perelman School of Medicine Standardized Patient Program to explore the novel use of telesimulation with standardized parents to train research staff to approach parents of critically ill children for informed consent. We describe the feasibility, learner acceptance, and financial costs of this novel intervention and performed a post hoc analysis to determine if this intervention improved study consent rates.
DESIGN: Observational, comparative effectiveness study.
SETTING: Heart And Lung Failure-Pediatric INsulin Titration study enrolling sites.
SUBJECTS: Research staff (at the remote site).
INTERVENTIONS: Individual 90-minute Skype telesimulation sessions with standardized parent and simulation facilitator (at the training site).
MEASUREMENTS AND MAIN RESULTS: Forty telesimulation sessions with 79 Heart And Lung Failure-Pediatric INsulin Titration research staff (participants) at 24 remote sites were conducted. Despite some technical delays, 40 out of 40 simulations (100%) were completed. Based on feedback surveys, 100% of respondents agreed (81% strongly agreed) that telesimulation sessions achieved intended learning objectives to prepare research staff to approach parents of eligible critically ill children to obtain informed consent. Additionally, 100% of respondents agreed (74% strongly agreed) that they would use lessons from the telesimulation when approaching parents to obtain informed consent for research. Telesimulation with standardized parents achieved lower financial costs (approximately $85 per session) compared with traditional in-person site visits for training research staff. There was no significant improvement in study consent rates with the intervention (pre: 46% vs post: 48%; p = 0.78).
CONCLUSIONS: Remote telesimulation with standardized parents is feasible, acceptable, and associated with lower financial costs to prepare research staff to obtain informed consent from parents of critically ill children eligible for clinical research trials. Despite this novel approach, Heart And Lung Failure-Pediatric INsulin Titration study consent rates did not improve, suggesting that other factors influence parental consent and decision making in complex multicenter clinical research trials.
| Errataetall: |
CommentIn: Pediatr Crit Care Med. 2020 Dec;21(12):1089-1090. - PMID 33278216 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
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| Enthalten in: |
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 21(2020), 12 vom: 01. Dez., Seite e1042-e1051 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
LaMarra, Denise [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 06.01.2021 Date Revised 31.05.2022 published: Print ClinicalTrials.gov: NCT01565941 CommentIn: Pediatr Crit Care Med. 2020 Dec;21(12):1089-1090. - PMID 33278216 Citation Status MEDLINE |
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| doi: |
10.1097/PCC.0000000000002484 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM313156042 |
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| 100 | 1 | |a LaMarra, Denise |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A Novel Framework Using Remote Telesimulation With Standardized Parents to Improve Research Staff Preparedness for Informed Consent in Pediatric Critical Care Research |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Completed 06.01.2021 | ||
| 500 | |a Date Revised 31.05.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a ClinicalTrials.gov: NCT01565941 | ||
| 500 | |a CommentIn: Pediatr Crit Care Med. 2020 Dec;21(12):1089-1090. - PMID 33278216 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: The Heart And Lung Failure-Pediatric INsulin Titration study was experiencing poor subject enrollment due to low rates of informed consent. Heart And Lung Failure-Pediatric INsulin Titration investigators collaborated with the Perelman School of Medicine Standardized Patient Program to explore the novel use of telesimulation with standardized parents to train research staff to approach parents of critically ill children for informed consent. We describe the feasibility, learner acceptance, and financial costs of this novel intervention and performed a post hoc analysis to determine if this intervention improved study consent rates | ||
| 520 | |a DESIGN: Observational, comparative effectiveness study | ||
| 520 | |a SETTING: Heart And Lung Failure-Pediatric INsulin Titration study enrolling sites | ||
| 520 | |a SUBJECTS: Research staff (at the remote site) | ||
| 520 | |a INTERVENTIONS: Individual 90-minute Skype telesimulation sessions with standardized parent and simulation facilitator (at the training site) | ||
| 520 | |a MEASUREMENTS AND MAIN RESULTS: Forty telesimulation sessions with 79 Heart And Lung Failure-Pediatric INsulin Titration research staff (participants) at 24 remote sites were conducted. Despite some technical delays, 40 out of 40 simulations (100%) were completed. Based on feedback surveys, 100% of respondents agreed (81% strongly agreed) that telesimulation sessions achieved intended learning objectives to prepare research staff to approach parents of eligible critically ill children to obtain informed consent. Additionally, 100% of respondents agreed (74% strongly agreed) that they would use lessons from the telesimulation when approaching parents to obtain informed consent for research. Telesimulation with standardized parents achieved lower financial costs (approximately $85 per session) compared with traditional in-person site visits for training research staff. There was no significant improvement in study consent rates with the intervention (pre: 46% vs post: 48%; p = 0.78) | ||
| 520 | |a CONCLUSIONS: Remote telesimulation with standardized parents is feasible, acceptable, and associated with lower financial costs to prepare research staff to obtain informed consent from parents of critically ill children eligible for clinical research trials. Despite this novel approach, Heart And Lung Failure-Pediatric INsulin Titration study consent rates did not improve, suggesting that other factors influence parental consent and decision making in complex multicenter clinical research trials | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a French, Jaclyn |e verfasserin |4 aut | |
| 700 | 1 | |a Bailey, Christine |e verfasserin |4 aut | |
| 700 | 1 | |a Sisko, Martha T |e verfasserin |4 aut | |
| 700 | 1 | |a Coughlin-Wells, Kerry |e verfasserin |4 aut | |
| 700 | 1 | |a Agus, Michael S D |e verfasserin |4 aut | |
| 700 | 1 | |a Srinivasan, Vijay |e verfasserin |4 aut | |
| 700 | 1 | |a Nadkarni, Vinay M |e verfasserin |4 aut | |
| 700 | 0 | |a Heart And Lung Failure—Pediatric INsulin Titration (HALF-PINT) Study Investigators |e verfasserin |4 aut | |
| 700 | 1 | |a Agus, Michael |e investigator |4 oth | |
| 700 | 1 | |a Wypij, David |e investigator |4 oth | |
| 700 | 1 | |a Asaro, Lisa |e investigator |4 oth | |
| 700 | 1 | |a Nadkarni, Vinay |e investigator |4 oth | |
| 700 | 1 | |a Srinivasan, Vijay |e investigator |4 oth | |
| 700 | 1 | |a Biagas, Katherine |e investigator |4 oth | |
| 700 | 1 | |a Mourani, Peter M |e investigator |4 oth | |
| 700 | 1 | |a Chima, Ranjit |e investigator |4 oth | |
| 700 | 1 | |a Thomas, Neal J |e investigator |4 oth | |
| 700 | 1 | |a Li, Simon |e investigator |4 oth | |
| 700 | 1 | |a Pinto, Alan |e investigator |4 oth | |
| 700 | 1 | |a Newth, Christopher |e investigator |4 oth | |
| 700 | 1 | |a Hassinger, Amanda |e investigator |4 oth | |
| 700 | 1 | |a Bysani, Kris |e investigator |4 oth | |
| 700 | 1 | |a Rehder, Kyle J |e investigator |4 oth | |
| 700 | 1 | |a Faustino, Edward Vincent |e investigator |4 oth | |
| 700 | 1 | |a Kandil, Sarah |e investigator |4 oth | |
| 700 | 1 | |a Hirshberg, Eliotte |e investigator |4 oth | |
| 700 | 1 | |a Wintergerst, Kupper |e investigator |4 oth | |
| 700 | 1 | |a Schwarz, Adam |e investigator |4 oth | |
| 700 | 1 | |a Bagdure, Dayanand |e investigator |4 oth | |
| 700 | 1 | |a Marsillio, Lauren |e investigator |4 oth | |
| 700 | 1 | |a Cvijanovich, Natalie |e investigator |4 oth | |
| 700 | 1 | |a Pham, Nga |e investigator |4 oth | |
| 700 | 1 | |a Quasney, Michael |e investigator |4 oth | |
| 700 | 1 | |a Flori, Heidi |e investigator |4 oth | |
| 700 | 1 | |a Federman, Myke |e investigator |4 oth | |
| 700 | 1 | |a Nett, Sholeen |e investigator |4 oth | |
| 700 | 1 | |a Pinto, Neethi |e investigator |4 oth | |
| 700 | 1 | |a Viteri, Shirley |e investigator |4 oth | |
| 700 | 1 | |a Schneider, James |e investigator |4 oth | |
| 700 | 1 | |a Medar, Shivanand |e investigator |4 oth | |
| 700 | 1 | |a Sapru, Anil |e investigator |4 oth | |
| 700 | 1 | |a McQuillen, Patrick |e investigator |4 oth | |
| 700 | 1 | |a Babbitt, Christopher |e investigator |4 oth | |
| 700 | 1 | |a Lin, John C |e investigator |4 oth | |
| 700 | 1 | |a Jouvet, Philippe |e investigator |4 oth | |
| 700 | 1 | |a Yanay, Ofer |e investigator |4 oth | |
| 700 | 1 | |a Allen, Christine |e investigator |4 oth | |
| 700 | 1 | |a Luckett, Peter |e investigator |4 oth | |
| 700 | 1 | |a Fackler, James |e investigator |4 oth | |
| 700 | 1 | |a Rozen, Thomas |e investigator |4 oth | |
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