Increased risk of SARS-CoV-2 infection in staff working across different care homes : enhanced CoVID-19 outbreak investigations in London care Homes
Copyright © 2020. Published by Elsevier Ltd..
BACKGROUND: Care homes have been disproportionately affected by the COVID-19 pandemic and continue to suffer large outbreaks even when community infection rates are declining, thus representing important pockets of transmission. We assessed occupational risk factors for SARS-CoV-2 infection among staff in six care homes experiencing a COVID-19 outbreak during the peak of the pandemic in London, England.
METHODS: Care home staff were tested for SARS-COV-2 infection by RT-PCR and asked to report any symptoms, their contact with residents and if they worked in different care homes. Whole genome sequencing (WGS) was performed on RT-PCR positive samples.
RESULTS: In total, 53 (21%) of 254 staff were SARS-CoV-2 positive but only 12/53 (23%) were symptomatic. Among staff working in a single care home, SARS-CoV-2 positivity was 15% (2/13), 16% (7/45) and 18% (30/169) in those reporting no, occasional and regular contact with residents. In contrast, staff working across different care homes (14/27, 52%) had a 3.0-fold (95% CI, 1.9-4.8; P<0.001) higher risk of SARS-CoV-2 positivity than staff working in single care homes (39/227, 17%). WGS identified SARS-CoV-2 clusters involving staff only, including some that included staff working across different care homes.
CONCLUSIONS: SARS-CoV-2 positivity was significantly higher among staff working across different care homes than those who were working in the same care home. We found local clusters of SARS-CoV-2 infection between staff only, including those with minimal resident contact. Infection control should be extended for all contact, including those between staff, whilst on care home premises.
| Errataetall: |
CommentIn: J Infect. 2021 Aug;83(2):e22-e24. - PMID 34116074 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:81 |
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| Enthalten in: |
The Journal of infection - 81(2020), 4 vom: 01. Okt., Seite 621-624 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ladhani, Shamez N [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 05.10.2020 Date Revised 22.02.2023 published: Print-Electronic CommentIn: J Infect. 2021 Aug;83(2):e22-e24. - PMID 34116074 Citation Status MEDLINE |
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| doi: |
10.1016/j.jinf.2020.07.027 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM313113904 |
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| 100 | 1 | |a Ladhani, Shamez N |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Increased risk of SARS-CoV-2 infection in staff working across different care homes |b enhanced CoVID-19 outbreak investigations in London care Homes |
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| 500 | |a CommentIn: J Infect. 2021 Aug;83(2):e22-e24. - PMID 34116074 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020. Published by Elsevier Ltd. | ||
| 520 | |a BACKGROUND: Care homes have been disproportionately affected by the COVID-19 pandemic and continue to suffer large outbreaks even when community infection rates are declining, thus representing important pockets of transmission. We assessed occupational risk factors for SARS-CoV-2 infection among staff in six care homes experiencing a COVID-19 outbreak during the peak of the pandemic in London, England | ||
| 520 | |a METHODS: Care home staff were tested for SARS-COV-2 infection by RT-PCR and asked to report any symptoms, their contact with residents and if they worked in different care homes. Whole genome sequencing (WGS) was performed on RT-PCR positive samples | ||
| 520 | |a RESULTS: In total, 53 (21%) of 254 staff were SARS-CoV-2 positive but only 12/53 (23%) were symptomatic. Among staff working in a single care home, SARS-CoV-2 positivity was 15% (2/13), 16% (7/45) and 18% (30/169) in those reporting no, occasional and regular contact with residents. In contrast, staff working across different care homes (14/27, 52%) had a 3.0-fold (95% CI, 1.9-4.8; P<0.001) higher risk of SARS-CoV-2 positivity than staff working in single care homes (39/227, 17%). WGS identified SARS-CoV-2 clusters involving staff only, including some that included staff working across different care homes | ||
| 520 | |a CONCLUSIONS: SARS-CoV-2 positivity was significantly higher among staff working across different care homes than those who were working in the same care home. We found local clusters of SARS-CoV-2 infection between staff only, including those with minimal resident contact. Infection control should be extended for all contact, including those between staff, whilst on care home premises | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a Care homes | |
| 650 | 4 | |a Occupational risk | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a Transmission | |
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| 700 | 1 | |a Janarthanan, Roshni |e verfasserin |4 aut | |
| 700 | 1 | |a Fok, Jonathan |e verfasserin |4 aut | |
| 700 | 1 | |a Crawley-Boevey, Emma |e verfasserin |4 aut | |
| 700 | 1 | |a Vusirikala, Amoolya |e verfasserin |4 aut | |
| 700 | 1 | |a Fernandez, Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Perez, Marina Sanchez |e verfasserin |4 aut | |
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| 700 | 1 | |a Chand, Meera |e verfasserin |4 aut | |
| 700 | 1 | |a Brown, Kevin |e verfasserin |4 aut | |
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