COVID-19 : a wreak havoc across the globe

Coronavirus disease (COVID-19) is an infectious airborne viral pneumonia caused by a novel virus belonging to the family coronaviridae. On February 11, 2019, the Internal Committee on Taxonomy of Virus (ICTV) announced the name of the novel virus as "severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One of the proteins present on its membrane i.e. the Spike protein is responsible for the attachment of the virus to the host. It spreads through the salivary droplets released when an infected person sneezes or coughs. The best way to slow down the disease is by protecting self by washing hands and using the disinfectant. Most of the infected people experience mild to moderate breathing issues. Serious illness might develop in people with underlying cardiovascular problems, diabetes and other immuno-compromised diseases. To date, there is no effective medicine available in the market which is effective in COVID-19. However, healthcare professionals are using ritonavir, flavipiravir, lopinavir, hydroxychloroquine and remdesivir. Along with the medicines, some countries are using convalescent plasma and mesenchymal stem cells for treatment. Till date, it has claimed millions of death worldwide. In this detailed review, we have discussed the structure of SARS-CoV-2, essential proteins, its lifecycle, transmission, symptoms, pathology, clinical features, diagnosis, prevention, treatment and epidemiology of the disease.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:129

Enthalten in:

Archives of physiology and biochemistry - 129(2023), 1 vom: 28. Feb., Seite 82-94

Sprache:

Englisch

Beteiligte Personen:

Rehman, Heena [VerfasserIn]
Ahmad, Md Iftekhar [VerfasserIn]

Links:

Volltext

Themen:

2494G1JF75
ACE2
Acute respiratory distress syndrome
COVID-19
Cellular and humoral immunity
Journal Article
Lopinavir
O3J8G9O825
Polymerase chain reaction
Real time reverse transciptase
Ritonavir
Spike protein

Anmerkungen:

Date Completed 06.02.2023

Date Revised 06.02.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/13813455.2020.1797105

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM313056536