Diagnostic groups and short-term outcomes in suspected COVID-19 cases treated in an emergency department
OBJECTIVES: The primary objective was to describe the clinical characteristics and 30-day mortality rates in emergency department patients with coronavirus disease 2019 (COVID-19) in different diagnostic groupings.
MATERIAL AND METHODS: Secondary analysis of the COVID-19 registry compiled by the emergency department of Hospital Clínico San Carlos in Madrid, Spain. We selected suspected COVID-19 cases treated in the emergency department between February 28 and March 31, 2020. The cases were grouped as follows: 1) suspected, no polymerase chain reaction (PCR) test (S/no-PCR); 2) suspected, negative PCR (S/PCR-); 3) suspected, positive PCR (S/PCR+); 4) highly suspected, no PCR, or negative PCR (HS/no or PCR-); and 5) highly suspected, positive PCR (HS/PCR+). We collected clinical, radiologic, and microbiologic data related to the emergency visit. The main outcome was 30-day all-cause mortality. Secondary outcomes were hospitalization and clinical severity of the episode.
RESULTS: A total of 1993 cases (90.9%) were included as follows: S/no-PCR, 17.2%; S/PCR-, 11.4%; S/PCR+, 22.1%; HS/no PCR or PCR-, 11.7%; and HS/PCR+, 37.6%. Short-term outcomes differed significantly in the different groups according to demographic characteristics; comorbidity and clinical, radiographic, analytical, and therapeutic variables. Thirty-day mortality was 11.5% (56.5% in hospitalized cases and 19.6% in cases classified as severe). The 2 HS categories and the S/PCR+ category had a greater adjusted risk for 30-day mortality and for having a clinically severe episode during hospitalization in comparison with S/PCR- cases. Only the 2 HS categories showed greater risk for hospitalization than the S/PCR- cases.
CONCLUSION: COVID-19 diagnostic groups differ according to clinical and laboratory characteristics, and the differences are associated with the 30-day prognosis.
| Errataetall: |
CommentIn: Emergencias. 2020 Ago;32(4):225-226. - PMID 32691998 |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:32 |
|---|---|
| Enthalten in: |
Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias - 32(2020), 4 vom: 21., Seite 242-252 |
| Sprache: |
Englisch |
|---|
| Weiterer Titel: |
Categorías diagnósticas y resultados a corto plazo en los pacientes con sospecha de COVID-19 atendidos en un servicio de urgencias |
|---|
| Beteiligte Personen: |
Martín-Sánchez, F Javier [VerfasserIn] |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
Date Completed 29.07.2020 Date Revised 18.12.2020 published: Print CommentIn: Emergencias. 2020 Ago;32(4):225-226. - PMID 32691998 Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM31268259X |
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| 100 | 1 | |a Martín-Sánchez, F Javier |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Diagnostic groups and short-term outcomes in suspected COVID-19 cases treated in an emergency department |
| 246 | 3 | 3 | |a Categorías diagnósticas y resultados a corto plazo en los pacientes con sospecha de COVID-19 atendidos en un servicio de urgencias |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 29.07.2020 | ||
| 500 | |a Date Revised 18.12.2020 | ||
| 500 | |a published: Print | ||
| 500 | |a CommentIn: Emergencias. 2020 Ago;32(4):225-226. - PMID 32691998 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVES: The primary objective was to describe the clinical characteristics and 30-day mortality rates in emergency department patients with coronavirus disease 2019 (COVID-19) in different diagnostic groupings | ||
| 520 | |a MATERIAL AND METHODS: Secondary analysis of the COVID-19 registry compiled by the emergency department of Hospital Clínico San Carlos in Madrid, Spain. We selected suspected COVID-19 cases treated in the emergency department between February 28 and March 31, 2020. The cases were grouped as follows: 1) suspected, no polymerase chain reaction (PCR) test (S/no-PCR); 2) suspected, negative PCR (S/PCR-); 3) suspected, positive PCR (S/PCR+); 4) highly suspected, no PCR, or negative PCR (HS/no or PCR-); and 5) highly suspected, positive PCR (HS/PCR+). We collected clinical, radiologic, and microbiologic data related to the emergency visit. The main outcome was 30-day all-cause mortality. Secondary outcomes were hospitalization and clinical severity of the episode | ||
| 520 | |a RESULTS: A total of 1993 cases (90.9%) were included as follows: S/no-PCR, 17.2%; S/PCR-, 11.4%; S/PCR+, 22.1%; HS/no PCR or PCR-, 11.7%; and HS/PCR+, 37.6%. Short-term outcomes differed significantly in the different groups according to demographic characteristics; comorbidity and clinical, radiographic, analytical, and therapeutic variables. Thirty-day mortality was 11.5% (56.5% in hospitalized cases and 19.6% in cases classified as severe). The 2 HS categories and the S/PCR+ category had a greater adjusted risk for 30-day mortality and for having a clinically severe episode during hospitalization in comparison with S/PCR- cases. Only the 2 HS categories showed greater risk for hospitalization than the S/PCR- cases | ||
| 520 | |a CONCLUSION: COVID-19 diagnostic groups differ according to clinical and laboratory characteristics, and the differences are associated with the 30-day prognosis | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a Emergency department | |
| 650 | 4 | |a Mortalidad | |
| 650 | 4 | |a Mortality | |
| 650 | 4 | |a PCR | |
| 650 | 4 | |a Polymerase chain reaction (PCR) | |
| 650 | 4 | |a SARS-CoV-2 | |
| 650 | 4 | |a SARS-Cov-2 | |
| 650 | 4 | |a Servicio de urgencias | |
| 700 | 1 | |a González Del Castillo, Juan |e verfasserin |4 aut | |
| 700 | 1 | |a Valls Carbó, Adrián |e verfasserin |4 aut | |
| 700 | 1 | |a López Picado, Amanda |e verfasserin |4 aut | |
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| 700 | 1 | |a Cozar López, Gabriel |e verfasserin |4 aut | |
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| 700 | 1 | |a Jerez Fernández, Pablo |e verfasserin |4 aut | |
| 700 | 1 | |a Del Toro, Enrique |e verfasserin |4 aut | |
| 700 | 1 | |a Cardassay, Eduardo |e verfasserin |4 aut | |
| 700 | 1 | |a Angós, Beatriz |e verfasserin |4 aut | |
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| 700 | 1 | |a Rodríguez Adrada, Esther |e verfasserin |4 aut | |
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| 700 | 1 | |a Elvira, Carlos |e verfasserin |4 aut | |
| 700 | 1 | |a García Briñón, Miguel Ángel |e verfasserin |4 aut | |
| 700 | 1 | |a Leal Pozuelo, José Mª |e verfasserin |4 aut | |
| 700 | 1 | |a Ortega, Luis |e verfasserin |4 aut | |
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| 700 | 1 | |a González Armengol, Juan Jorge |e verfasserin |4 aut | |
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