Early detection of euglycemic ketoacidosis during thoracic surgery associated with empagliflozin in a patient with type 2 diabetes : A case report
© 2020 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd..
We report the first case of intraoperatively detected euglycemic diabetic ketoacidosis (DKA) associated with sodium-glucose cotransporter 2 inhibitors during thoracic surgery. A 59-year-old man had a 12-year history of type 2 diabetes mellitus treated with insulin and empagliflozin. The patient developed bacterial empyema and was initiated with antibiotics at a local hospital. Owing to the persistence of his symptoms, he was transferred to our hospital after the medication of empagliflozin the day before surgery. After overnight fasting, the patient underwent thoracoscopic debridement and intrathoracic lavage surgery. During this surgery, he was noted to have euglycemic ketosis and acidosis, and diagnosed as euglycemic DKA. Immediately after the consultation in our department, the patient underwent treatment for DKA. He awoke from anesthesia normally and showed no symptoms of DKA. DKA gradually resolved over the next 24 h. Early identification and management are critical for rapid recovery from perioperative euglycemic DKA associated with sodium-glucose cotransporter 2 inhibitors, especially during thoracic surgery.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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Enthalten in: |
Journal of diabetes investigation - 12(2021), 4 vom: 19. Apr., Seite 664-667 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Kitahara, Chie [VerfasserIn] |
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Links: |
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Themen: |
Benzhydryl Compounds |
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Anmerkungen: |
Date Completed 31.01.2022 Date Revised 31.01.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1111/jdi.13365 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM312626207 |
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520 | |a We report the first case of intraoperatively detected euglycemic diabetic ketoacidosis (DKA) associated with sodium-glucose cotransporter 2 inhibitors during thoracic surgery. A 59-year-old man had a 12-year history of type 2 diabetes mellitus treated with insulin and empagliflozin. The patient developed bacterial empyema and was initiated with antibiotics at a local hospital. Owing to the persistence of his symptoms, he was transferred to our hospital after the medication of empagliflozin the day before surgery. After overnight fasting, the patient underwent thoracoscopic debridement and intrathoracic lavage surgery. During this surgery, he was noted to have euglycemic ketosis and acidosis, and diagnosed as euglycemic DKA. Immediately after the consultation in our department, the patient underwent treatment for DKA. He awoke from anesthesia normally and showed no symptoms of DKA. DKA gradually resolved over the next 24 h. Early identification and management are critical for rapid recovery from perioperative euglycemic DKA associated with sodium-glucose cotransporter 2 inhibitors, especially during thoracic surgery | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a Empagliflozin | |
650 | 4 | |a Intraoperative euglycemic ketoacidosis | |
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650 | 7 | |a Glucosides |2 NLM | |
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700 | 1 | |a Kishimoto, Shohei |e verfasserin |4 aut | |
700 | 1 | |a Matsuno, Shohei |e verfasserin |4 aut | |
700 | 1 | |a Uraki, Shinsuke |e verfasserin |4 aut | |
700 | 1 | |a Takeshima, Ken |e verfasserin |4 aut | |
700 | 1 | |a Furukawa, Yasushi |e verfasserin |4 aut | |
700 | 1 | |a Inaba, Hidefumi |e verfasserin |4 aut | |
700 | 1 | |a Iwakura, Hiroshi |e verfasserin |4 aut | |
700 | 1 | |a Ariyasu, Hiroyuki |e verfasserin |4 aut | |
700 | 1 | |a Furuta, Hiroto |e verfasserin |4 aut | |
700 | 1 | |a Nishi, Masahiro |e verfasserin |4 aut | |
700 | 1 | |a Akamizu, Takashi |e verfasserin |4 aut | |
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