Current pharmacological modalities for management of novel coronavirus disease 2019 (COVID-19) and the rationale for their utilization : A review

© 2020 John Wiley & Sons, Ltd..

SARS-CoV-2 has caused a pandemic which is putting strain on the health-care system and global economy. There is much pressure to develop both preventative and curative therapies for SARS-CoV-2 as there is no evidence to support therapies to improve outcomes in patients with SARS-CoV-2. Medications that inhibit certain steps of virus life cycle that are currently used to treat other illnesses such as Malaria, Ebola, HIV and Hepatitis C are being studied for use against SARS-CoV-2. To date, data is limited for medications that facilitate clinical improvement of COVID-19 infections.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Reviews in medical virology - 30(2020), 5 vom: 15. Sept., Seite e2136

Sprache:

Englisch

Beteiligte Personen:

Giovane, Richard A [VerfasserIn]
Rezai, Shadi [VerfasserIn]
Cleland, Ellen [VerfasserIn]
Henderson, Cassandra E [VerfasserIn]

Links:

Volltext

Themen:

0FD207WKDU
2019-nCoV
2494G1JF75
3QKI37EEHE
415SHH325A
4QWG6N8QKH
4V7M9137X9
93M09WW4RU
ACE2 protein, human
Acetazolamide
Acute respiratory distress syndrome (ARDS)
Adenosine Monophosphate
Alanine
Angiotensin-Converting Enzyme 2
Antibodies, Monoclonal, Humanized
Antiviral Agents
Autoimmune
COVID-19
Camostat
Camostat mesylate
Chloroquine
Drug Combinations
EC 3.4.15.1
EC 3.4.17.23
Esters
Gabexate
Guanidines
High altitude pulmonary edema (HAPE)
Hydroxychloroquine
I031V2H011
Indoles
Journal Article
Lopinavir
Lopinavir/Ritonavir
Lopinavir-ritonavir drug combination
Novel coronavirus 2019
O3J8G9O825
OF5P57N2ZX
Pandemic
Peptidyl-Dipeptidase A
RNA-dependent RNA polymerase inhibitors
Remdesivir
Review
Ritonavir
SARS CoV-2
SARS coronavirus (SARS-CoV)
Severe acute respiratory syndrome (SARS)
Spike Glycoprotein, Coronavirus
Spike protein, SARS-CoV-2
Tocilizumab
Umifenovir

Anmerkungen:

Date Completed 01.10.2020

Date Revised 05.10.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/rmv.2136

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM312215258