SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines
The advent of COVID-19, has posed a risk that human respiratory samples containing human influenza viruses may also contain SARS-CoV-2. This potential risk may lead to SARS-CoV-2 contaminating conventional influenza vaccine production platforms as respiratory samples are used to directly inoculate embryonated hen's eggs and continuous cell lines that are used to isolate and produce influenza vaccines. We investigated the ability of these substrates to propagate SARS-CoV-2 and found that neither could support SARS-CoV-2 replication.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 25(2020), 25 vom: 16. Juni |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Barr, Ian G [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 08.07.2020 Date Revised 15.09.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.2807/1560-7917.ES.2020.25.25.2001122 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM311917763 |
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| 100 | 1 | |a Barr, Ian G |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Completed 08.07.2020 | ||
| 500 | |a Date Revised 15.09.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The advent of COVID-19, has posed a risk that human respiratory samples containing human influenza viruses may also contain SARS-CoV-2. This potential risk may lead to SARS-CoV-2 contaminating conventional influenza vaccine production platforms as respiratory samples are used to directly inoculate embryonated hen's eggs and continuous cell lines that are used to isolate and produce influenza vaccines. We investigated the ability of these substrates to propagate SARS-CoV-2 and found that neither could support SARS-CoV-2 replication | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Influenza, SARS-CoV-2, vaccine, respiratory, air-borne infections, viral infections, influenza | |
| 650 | 4 | |a severe acute respiratory syndrome – SARS, influenza virus, biosafety, vaccines and immunisation, laboratory | |
| 650 | 7 | |a Influenza Vaccines |2 NLM | |
| 650 | 7 | |a Receptors, Virus |2 NLM | |
| 700 | 1 | |a Rynehart, Cleve |e verfasserin |4 aut | |
| 700 | 1 | |a Whitney, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Druce, Julian |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin |d 1995 |g 25(2020), 25 vom: 16. Juni |w (DE-627)NLM115683283 |x 1560-7917 |7 nnns |
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| 856 | 4 | 0 | |u http://dx.doi.org/10.2807/1560-7917.ES.2020.25.25.2001122 |3 Volltext |
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