Steep Rebound of Chloroquine-Sensitive Plasmodium falciparum in Zimbabwe
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com..
Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact of drug policy on antimalarial resistance.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:223 |
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| Enthalten in: |
The Journal of infectious diseases - 223(2021), 2 vom: 03. Feb., Seite 306-309 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Mharakurwa, Sungano [VerfasserIn] |
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| Links: |
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| Themen: |
886U3H6UFF |
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| Anmerkungen: |
Date Completed 06.09.2021 Date Revised 06.09.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.1093/infdis/jiaa368 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM311722903 |
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| 520 | |a © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissionsoup.com. | ||
| 520 | |a Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact of drug policy on antimalarial resistance | ||
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| 700 | 1 | |a Matimba, Charmaine |e verfasserin |4 aut | |
| 700 | 1 | |a Gara, Tanatswa Xuxa |e verfasserin |4 aut | |
| 700 | 1 | |a Makuwaza, Aramu |e verfasserin |4 aut | |
| 700 | 1 | |a Maponga, Gladys |e verfasserin |4 aut | |
| 700 | 1 | |a Munyati, Shungu |e verfasserin |4 aut | |
| 700 | 1 | |a Gwanzura, Lovemore |e verfasserin |4 aut | |
| 700 | 1 | |a Mutambu, Susan L |e verfasserin |4 aut | |
| 700 | 1 | |a Mason, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Kobayashi, Tamaki |e verfasserin |4 aut | |
| 700 | 1 | |a Midzi, Nicholas |e verfasserin |4 aut | |
| 700 | 1 | |a Moss, William J |e verfasserin |4 aut | |
| 700 | 1 | |a Ippolito, Matthew M |e verfasserin |4 aut | |
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