Epidemiology and clinical course of COVID-19 in Shanghai, China
Background: Novel coronavirus pneumonia (COVID-19) is prevalent around the world. We aimed to describe epidemiological features and clinical course in Shanghai. Methods: We retrospectively analysed 325 cases admitted at Shanghai Public Health Clinical Center, between January 20 and February 29, 2020. Results: 47.4% (154/325) had visited Wuhan within 2 weeks of illness onset. 57.2% occurred in 67 clusters; 40% were situated within 53 family clusters. 83.7% developed fever during the disease course. Median times from onset to first medical care, hospitalization and negative detection of nucleic acid by nasopharyngeal swab were 1, 4 and 8 days. Patients with mild disease using glucocorticoid tended to have longer viral shedding in blood and feces. At admission, 69.8% presented with lymphopenia and 38.8% had elevated D-dimers. Pneumonia was identified in 97.5% (314/322) of cases by chest CT scan. Severe-critical patients were 8% with a median time from onset to critical disease of 10.5 days. Half required oxygen therapy and 7.1% high-flow nasal oxygen. The case fatality rate was 0.92% with median time from onset to death of 16 days. Conclusion: COVID-19 cases in Shanghai were imported. Rapid identification, and effective control measures helped to contain the outbreak and prevent community transmission.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
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| Enthalten in: |
Emerging microbes & infections - 9(2020), 1 vom: 04. Dez., Seite 1537-1545 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Shen, Yinzhong [VerfasserIn] |
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| Links: |
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| Themen: |
COVID-19 |
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| Anmerkungen: |
Date Completed 14.07.2020 Date Revised 05.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1080/22221751.2020.1787103 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM311518834 |
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| 245 | 1 | 0 | |a Epidemiology and clinical course of COVID-19 in Shanghai, China |
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| 520 | |a Background: Novel coronavirus pneumonia (COVID-19) is prevalent around the world. We aimed to describe epidemiological features and clinical course in Shanghai. Methods: We retrospectively analysed 325 cases admitted at Shanghai Public Health Clinical Center, between January 20 and February 29, 2020. Results: 47.4% (154/325) had visited Wuhan within 2 weeks of illness onset. 57.2% occurred in 67 clusters; 40% were situated within 53 family clusters. 83.7% developed fever during the disease course. Median times from onset to first medical care, hospitalization and negative detection of nucleic acid by nasopharyngeal swab were 1, 4 and 8 days. Patients with mild disease using glucocorticoid tended to have longer viral shedding in blood and feces. At admission, 69.8% presented with lymphopenia and 38.8% had elevated D-dimers. Pneumonia was identified in 97.5% (314/322) of cases by chest CT scan. Severe-critical patients were 8% with a median time from onset to critical disease of 10.5 days. Half required oxygen therapy and 7.1% high-flow nasal oxygen. The case fatality rate was 0.92% with median time from onset to death of 16 days. Conclusion: COVID-19 cases in Shanghai were imported. Rapid identification, and effective control measures helped to contain the outbreak and prevent community transmission | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Sun, Danfeng |e verfasserin |4 aut | |
| 700 | 1 | |a Ling, Yun |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Feng |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Tao |e verfasserin |4 aut | |
| 700 | 1 | |a Qian, Zhiping |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Yuyi |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Qingnian |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Li |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Qin |e verfasserin |4 aut | |
| 700 | 1 | |a Shan, Fei |e verfasserin |4 aut | |
| 700 | 1 | |a Xu, Lie |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Zhaoqin |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Zhigang |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Shenyang |e verfasserin |4 aut | |
| 700 | 1 | |a Shi, Yuxin |e verfasserin |4 aut | |
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| 700 | 1 | |a Mendelsohn, Joshua B |e verfasserin |4 aut | |
| 700 | 1 | |a Zhu, Tongyu |e verfasserin |4 aut | |
| 700 | 1 | |a Lu, Hongzhou |e verfasserin |4 aut | |
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