Nivolumab-Induced Bullous Pemphigoid Managed without Drug Withdrawal
Copyright: © 2020 Indian Journal of Dermatology..
The widespread use of anti-programmed cell death receptor-1 (PD-1) agents has shed light to unusual immune-related adverse effects, especially affecting the skin. We report a case of bullous pemphigoid secondary to nivolumab therapy for metastatic renal carcinoma with a previously unreported complete response to clobetasol ointment alone. The autoimmune blistering disease was successfully treated without oral corticosteroids, and the anti-PD-1 agent could be maintained without recurrence of the skin lesions. Topical therapy remains a good option in selected, mild-to-moderate cases of induced bullous pemphigoid.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
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| Enthalten in: |
Indian journal of dermatology - 65(2020), 3 vom: 22. Mai, Seite 214-216 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Munera-Campos, Mónica [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-programmed cell death receptor-1 |
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| Anmerkungen: |
Date Revised 23.06.2020 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4103/ijd.IJD_321_18 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM311441882 |
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| 520 | |a The widespread use of anti-programmed cell death receptor-1 (PD-1) agents has shed light to unusual immune-related adverse effects, especially affecting the skin. We report a case of bullous pemphigoid secondary to nivolumab therapy for metastatic renal carcinoma with a previously unreported complete response to clobetasol ointment alone. The autoimmune blistering disease was successfully treated without oral corticosteroids, and the anti-PD-1 agent could be maintained without recurrence of the skin lesions. Topical therapy remains a good option in selected, mild-to-moderate cases of induced bullous pemphigoid | ||
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