SARS-CoV-2 coinfections : Could influenza and the common cold be beneficial?

© 2020 Wiley Periodicals LLC..

The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread around the world, causing serious illness and death and creating a heavy burden on the healthcare systems of many countries. Since the virus first emerged in late November 2019, its spread has coincided with peak circulation of several seasonal respiratory viruses, yet some studies have noted limited coinfections between SARS-CoV-2 and other viruses. We use a mathematical model of viral coinfection to study SARS-CoV-2 coinfections, finding that SARS-CoV-2 replication is easily suppressed by many common respiratory viruses. According to our model, this suppression is because SARS-CoV-2 has a lower growth rate (1.8/d) than the other viruses examined in this study. The suppression of SARS-CoV-2 by other pathogens could have implications for the timing and severity of a second wave.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:92

Enthalten in:

Journal of medical virology - 92(2020), 11 vom: 30. Nov., Seite 2623-2630

Sprache:

Englisch

Beteiligte Personen:

Pinky, Lubna [VerfasserIn]
Dobrovolny, Hana M [VerfasserIn]

Links:

Volltext

Themen:

Computer modeling
Human metapneumovirus
Human rhinovirus
Influenza virus
Journal Article
Respiratory syncytial virus
SARS coronavirus

Anmerkungen:

Date Completed 24.12.2020

Date Revised 16.07.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/jmv.26098

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM311364578