Effects of Positioning on Cough Peak Flow and Muscular Electromyographic Activation in Duchenne Muscular Dystrophy
Copyright © 2020 by Daedalus Enterprises..
BACKGROUND: Advanced stages of Duchenne muscular dystrophy (DMD) result in muscle weakness and the inability to generate an effective cough. Several factors influence the effectiveness of cough in patients with DMD. The aim of this study was to assess whether differences in positioning affect cough peak flow (CPF) and muscular electromyographic activation in subjects with DMD compared with paired healthy subjects.
METHODS: Optoelectronic plethysmography and surface electromyography were used to assess chest wall volumes, chest wall inspiratory capacity, CPF, breathing pattern, and electromyographic activity of sternocleidomastoid, scalene, rectus abdominis, and external oblique muscles during inspiratory and expiratory cough phases in the supine position, supine position with headrest raised at 45°, and sitting with back support at 80° in 12 subjects with DMD and 12 healthy subjects.
RESULTS: Subjects with DMD had lower CPF (P < .01) in comparison to control subjects in all positions; the DMD group also exhibited lower CPF (P = .045) in the supine position versus 80°. Moreover, the relative volume contributions of the rib cage and abdominal compartments to tidal volume modified significantly with posture. The electromyographic activity during inspiratory and expiratory cough phases was lower in subjects with DMD compared to healthy subjects for all evaluated muscles (P < .05), but no significant differences were observed with posture change.
CONCLUSIONS: In subjects with DMD, posture influenced CPF and the relative contribution of the rib cage and abdominal compartments to tidal volume. However, muscular electromyographic activation was not influenced by posture in subjects with DMD and healthy subjects.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:65 |
|---|---|
| Enthalten in: |
Respiratory care - 65(2020), 11 vom: 16. Nov., Seite 1668-1677 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Marques, Layana [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Cough |
|---|
| Anmerkungen: |
Date Completed 25.02.2021 Date Revised 25.02.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.4187/respcare.07426 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM311253334 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM311253334 | ||
| 003 | DE-627 | ||
| 005 | 20231225141847.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.4187/respcare.07426 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1037.xml |
| 035 | |a (DE-627)NLM311253334 | ||
| 035 | |a (NLM)32546537 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Marques, Layana |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of Positioning on Cough Peak Flow and Muscular Electromyographic Activation in Duchenne Muscular Dystrophy |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 25.02.2021 | ||
| 500 | |a Date Revised 25.02.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 by Daedalus Enterprises. | ||
| 520 | |a BACKGROUND: Advanced stages of Duchenne muscular dystrophy (DMD) result in muscle weakness and the inability to generate an effective cough. Several factors influence the effectiveness of cough in patients with DMD. The aim of this study was to assess whether differences in positioning affect cough peak flow (CPF) and muscular electromyographic activation in subjects with DMD compared with paired healthy subjects | ||
| 520 | |a METHODS: Optoelectronic plethysmography and surface electromyography were used to assess chest wall volumes, chest wall inspiratory capacity, CPF, breathing pattern, and electromyographic activity of sternocleidomastoid, scalene, rectus abdominis, and external oblique muscles during inspiratory and expiratory cough phases in the supine position, supine position with headrest raised at 45°, and sitting with back support at 80° in 12 subjects with DMD and 12 healthy subjects | ||
| 520 | |a RESULTS: Subjects with DMD had lower CPF (P < .01) in comparison to control subjects in all positions; the DMD group also exhibited lower CPF (P = .045) in the supine position versus 80°. Moreover, the relative volume contributions of the rib cage and abdominal compartments to tidal volume modified significantly with posture. The electromyographic activity during inspiratory and expiratory cough phases was lower in subjects with DMD compared to healthy subjects for all evaluated muscles (P < .05), but no significant differences were observed with posture change | ||
| 520 | |a CONCLUSIONS: In subjects with DMD, posture influenced CPF and the relative contribution of the rib cage and abdominal compartments to tidal volume. However, muscular electromyographic activation was not influenced by posture in subjects with DMD and healthy subjects | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Duchenne muscular dystrophy | |
| 650 | 4 | |a cough | |
| 650 | 4 | |a electromyography | |
| 650 | 4 | |a plethysmography | |
| 650 | 4 | |a respiratory muscles | |
| 700 | 1 | |a de Freitas Fregonezi, Guilherme Augusto |e verfasserin |4 aut | |
| 700 | 1 | |a Santos, Ilsa Priscila |e verfasserin |4 aut | |
| 700 | 1 | |a Marcelino, Ana Aline |e verfasserin |4 aut | |
| 700 | 1 | |a Medeiros da Fonsêca, Jéssica Danielle |e verfasserin |4 aut | |
| 700 | 1 | |a Dourado-Júnior, Mario Emílio Teixeira |e verfasserin |4 aut | |
| 700 | 1 | |a Aliverti, Andrea |e verfasserin |4 aut | |
| 700 | 1 | |a Sarmento, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Resqueti, Vanessa Regiane |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Respiratory care |d 1974 |g 65(2020), 11 vom: 16. Nov., Seite 1668-1677 |w (DE-627)NLM07486520X |x 1943-3654 |7 nnns |
| 773 | 1 | 8 | |g volume:65 |g year:2020 |g number:11 |g day:16 |g month:11 |g pages:1668-1677 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.4187/respcare.07426 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 65 |j 2020 |e 11 |b 16 |c 11 |h 1668-1677 | ||