The Fourth International Workshop on Clinical Transplant Tolerance

© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons..

The International Workshop on Clinical Transplant Tolerance is a biennial meeting that aims to provide an update on the progress of studies of immunosuppression minimization or withdrawal in solid organ transplantation. The Fourth International Workshop on Clinical Tolerance was held in Pittsburgh, Pennsylvania, September 5-6, 2019. This report is a summary of presentations on the status of clinical trials designed to minimize or withdraw immunosuppressive drugs in kidney, liver, and lung transplantation without subsequent evidence of rejection. All protocols had in common the use of donor or recipient cell therapy combined with organ transplantation. The workshop also included presentations of mechanistic studies designed to improve understanding of the cellular and molecular basis of tolerance and to identify potential predictors/biomarkers of tolerance. Strategies to enhance the safety of hematopoietic cell transplantation and to improve patient selection/risk stratification for clinical trials were also discussed.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 21(2021), 1 vom: 14. Jan., Seite 21-31

Sprache:

Englisch

Beteiligte Personen:

Issa, Fadi [VerfasserIn]
Strober, Samuel [VerfasserIn]
Leventhal, Joseph R [VerfasserIn]
Kawai, Tatsuo [VerfasserIn]
Kaufman, Dixon B [VerfasserIn]
Levitsky, Josh [VerfasserIn]
Sykes, Megan [VerfasserIn]
Mas, Valeria [VerfasserIn]
Wood, Kathryn J [VerfasserIn]
Bridges, Nancy [VerfasserIn]
Welniak, Lisbeth A [VerfasserIn]
Chandran, Sindhu [VerfasserIn]
Madsen, Joren C [VerfasserIn]
Nickerson, Peter [VerfasserIn]
Demetris, Anthony J [VerfasserIn]
Lakkis, Fadi G [VerfasserIn]
Thomson, Angus W [VerfasserIn]

Links:

Volltext

Themen:

Clinical research/practice
Clinical trial
Immune regulation
Immunosuppression/immune modulation
Immunosuppressive Agents
Journal Article
Kidney transplantation/nephrology
Liver transplantation/hepatology
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Tolerance: chimerism
Tolerance: clinical

Anmerkungen:

Date Completed 18.06.2021

Date Revised 15.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/ajt.16139

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM31108897X