Risks to healthcare workers following tracheal intubation of patients with COVID-19 : a prospective international multicentre cohort study
© 2020 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists..
Healthcare workers involved in aerosol-generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID-19. However, the magnitude of this risk is unknown. We conducted a prospective international multicentre cohort study recruiting healthcare workers participating in tracheal intubation of patients with suspected or confirmed COVID-19. Information on tracheal intubation episodes, personal protective equipment use and subsequent provider health status was collected via self-reporting. The primary endpoint was the incidence of laboratory-confirmed COVID-19 diagnosis or new symptoms requiring self-isolation or hospitalisation after a tracheal intubation episode. Cox regression analysis examined associations between the primary endpoint and healthcare worker characteristics, procedure-related factors and personal protective equipment use. Between 23 March and 2 June 2020, 1718 healthcare workers from 503 hospitals in 17 countries reported 5148 tracheal intubation episodes. The overall incidence of the primary endpoint was 10.7% over a median (IQR [range]) follow-up of 32 (18-48 [0-116]) days. The cumulative incidence within 7, 14 and 21 days of the first tracheal intubation episode was 3.6%, 6.1% and 8.5%, respectively. The risk of the primary endpoint varied by country and was higher in women, but was not associated with other factors. Around 1 in 10 healthcare workers involved in tracheal intubation of patients with suspected or confirmed COVID-19 subsequently reported a COVID-19 outcome. This has human resource implications for institutional capacity to deliver essential healthcare services, and wider societal implications for COVID-19 transmission.
| Errataetall: |
CommentIn: Anaesthesia. 2021 Mar;76 Suppl 3:3-4. - PMID 32638349 |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:75 |
|---|---|
| Enthalten in: |
Anaesthesia - 75(2020), 11 vom: 01. Nov., Seite 1437-1447 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
El-Boghdadly, K [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Airway |
|---|
| Anmerkungen: |
Date Completed 03.11.2020 Date Revised 16.07.2022 published: Print-Electronic CommentIn: Anaesthesia. 2021 Mar;76 Suppl 3:3-4. - PMID 32638349 Citation Status MEDLINE |
|---|
| doi: |
10.1111/anae.15170 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM310962056 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM310962056 | ||
| 003 | DE-627 | ||
| 005 | 20231225141227.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/anae.15170 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1036.xml |
| 035 | |a (DE-627)NLM310962056 | ||
| 035 | |a (NLM)32516833 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a El-Boghdadly, K |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Risks to healthcare workers following tracheal intubation of patients with COVID-19 |b a prospective international multicentre cohort study |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 03.11.2020 | ||
| 500 | |a Date Revised 16.07.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: Anaesthesia. 2021 Mar;76 Suppl 3:3-4. - PMID 32638349 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists. | ||
| 520 | |a Healthcare workers involved in aerosol-generating procedures, such as tracheal intubation, may be at elevated risk of acquiring COVID-19. However, the magnitude of this risk is unknown. We conducted a prospective international multicentre cohort study recruiting healthcare workers participating in tracheal intubation of patients with suspected or confirmed COVID-19. Information on tracheal intubation episodes, personal protective equipment use and subsequent provider health status was collected via self-reporting. The primary endpoint was the incidence of laboratory-confirmed COVID-19 diagnosis or new symptoms requiring self-isolation or hospitalisation after a tracheal intubation episode. Cox regression analysis examined associations between the primary endpoint and healthcare worker characteristics, procedure-related factors and personal protective equipment use. Between 23 March and 2 June 2020, 1718 healthcare workers from 503 hospitals in 17 countries reported 5148 tracheal intubation episodes. The overall incidence of the primary endpoint was 10.7% over a median (IQR [range]) follow-up of 32 (18-48 [0-116]) days. The cumulative incidence within 7, 14 and 21 days of the first tracheal intubation episode was 3.6%, 6.1% and 8.5%, respectively. The risk of the primary endpoint varied by country and was higher in women, but was not associated with other factors. Around 1 in 10 healthcare workers involved in tracheal intubation of patients with suspected or confirmed COVID-19 subsequently reported a COVID-19 outcome. This has human resource implications for institutional capacity to deliver essential healthcare services, and wider societal implications for COVID-19 transmission | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a airway | |
| 650 | 4 | |a coronavirus | |
| 650 | 4 | |a healthcare workers | |
| 650 | 4 | |a intubation | |
| 700 | 1 | |a Wong, D J N |e verfasserin |4 aut | |
| 700 | 1 | |a Owen, R |e verfasserin |4 aut | |
| 700 | 1 | |a Neuman, M D |e verfasserin |4 aut | |
| 700 | 1 | |a Pocock, S |e verfasserin |4 aut | |
| 700 | 1 | |a Carlisle, J B |e verfasserin |4 aut | |
| 700 | 1 | |a Johnstone, C |e verfasserin |4 aut | |
| 700 | 1 | |a Andruszkiewicz, P |e verfasserin |4 aut | |
| 700 | 1 | |a Baker, P A |e verfasserin |4 aut | |
| 700 | 1 | |a Biccard, B M |e verfasserin |4 aut | |
| 700 | 1 | |a Bryson, G L |e verfasserin |4 aut | |
| 700 | 1 | |a Chan, M T V |e verfasserin |4 aut | |
| 700 | 1 | |a Cheng, M H |e verfasserin |4 aut | |
| 700 | 1 | |a Chin, K J |e verfasserin |4 aut | |
| 700 | 1 | |a Coburn, M |e verfasserin |4 aut | |
| 700 | 1 | |a Jonsson Fagerlund, M |e verfasserin |4 aut | |
| 700 | 1 | |a Myatra, S N |e verfasserin |4 aut | |
| 700 | 1 | |a Myles, P S |e verfasserin |4 aut | |
| 700 | 1 | |a O'Sullivan, E |e verfasserin |4 aut | |
| 700 | 1 | |a Pasin, L |e verfasserin |4 aut | |
| 700 | 1 | |a Shamim, F |e verfasserin |4 aut | |
| 700 | 1 | |a van Klei, W A |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmad, I |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Anaesthesia |d 1947 |g 75(2020), 11 vom: 01. Nov., Seite 1437-1447 |w (DE-627)NLM000046280 |x 1365-2044 |7 nnns |
| 773 | 1 | 8 | |g volume:75 |g year:2020 |g number:11 |g day:01 |g month:11 |g pages:1437-1447 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/anae.15170 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 75 |j 2020 |e 11 |b 01 |c 11 |h 1437-1447 | ||