Prevalence of hepatitis B virus infection and associated risk factors among pregnant women attending antenatal clinic in Mulago Hospital, Uganda : a cross-sectional study
© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ..
AIM: To determine the prevalence and factors associated with hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital.
DESIGN: Cross-sectional observational study.
SETTING: Mulago National Referral Hospital, Uganda, antenatal clinic.
PARTICIPANTS: We randomly selected 340 pregnant women attending their first antenatal visit at Mulago Hospital antenatal clinic.
PRIMARY OUTCOME: Hepatitis B surface antigen positivity.
RESULTS: We recruited 340 participants, with a mean age of 27±5.7 years, and a median gravidity of 3. The prevalence of hepatitis B virus infection among pregnant women attending the antenatal clinic in Mulago Hospital, in our study, was 2.9% (95% CI 1.58% to 5.40%, n=10). Factors positively associated with hepatitis B virus infection were: marital status (adjusted OR (aOR)=11.37, p=0.002), having a hepatitis B positive family member (aOR=49.52, p<0.001) and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient (aOR=61.69, p=0.015). Other factors such as age, socioeconomic status, number of sexual partners, HIV serostatus, piercing of ears and history of blood transfusion were not significantly associated with hepatitis B virus infection in this study.
CONCLUSION: The prevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital was of intermediate endemicity. We found that marital status, having a hepatitis B positive family member at home and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient were independently associated with hepatitis B infection. Factors such as age, HIV status, history of blood transfusion, piercing of ears and social status were not associated with hepatitis B status in this study.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
BMJ open - 10(2020), 6 vom: 03. Juni, Seite e033043 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kayondo, Simon Peter [VerfasserIn] |
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| Links: |
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| Themen: |
Hepatitis B |
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| Anmerkungen: |
Date Completed 17.02.2021 Date Revised 30.03.2024 published: Electronic Citation Status MEDLINE |
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| doi: |
10.1136/bmjopen-2019-033043 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM310788323 |
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| 100 | 1 | |a Kayondo, Simon Peter |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prevalence of hepatitis B virus infection and associated risk factors among pregnant women attending antenatal clinic in Mulago Hospital, Uganda |b a cross-sectional study |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Completed 17.02.2021 | ||
| 500 | |a Date Revised 30.03.2024 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. | ||
| 520 | |a AIM: To determine the prevalence and factors associated with hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital | ||
| 520 | |a DESIGN: Cross-sectional observational study | ||
| 520 | |a SETTING: Mulago National Referral Hospital, Uganda, antenatal clinic | ||
| 520 | |a PARTICIPANTS: We randomly selected 340 pregnant women attending their first antenatal visit at Mulago Hospital antenatal clinic | ||
| 520 | |a PRIMARY OUTCOME: Hepatitis B surface antigen positivity | ||
| 520 | |a RESULTS: We recruited 340 participants, with a mean age of 27±5.7 years, and a median gravidity of 3. The prevalence of hepatitis B virus infection among pregnant women attending the antenatal clinic in Mulago Hospital, in our study, was 2.9% (95% CI 1.58% to 5.40%, n=10). Factors positively associated with hepatitis B virus infection were: marital status (adjusted OR (aOR)=11.37, p=0.002), having a hepatitis B positive family member (aOR=49.52, p<0.001) and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient (aOR=61.69, p=0.015). Other factors such as age, socioeconomic status, number of sexual partners, HIV serostatus, piercing of ears and history of blood transfusion were not significantly associated with hepatitis B virus infection in this study | ||
| 520 | |a CONCLUSION: The prevalence of hepatitis B virus infection among pregnant women attending antenatal clinic in Mulago Hospital was of intermediate endemicity. We found that marital status, having a hepatitis B positive family member at home and having had a blood or body fluid splash to mucous membranes from a hepatitis B positive patient were independently associated with hepatitis B infection. Factors such as age, HIV status, history of blood transfusion, piercing of ears and social status were not associated with hepatitis B status in this study | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a hepatitis B | |
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| 650 | 4 | |a prevalence | |
| 700 | 1 | |a Byamugisha, Josaphat K |e verfasserin |4 aut | |
| 700 | 1 | |a Ntuyo, Peter |e verfasserin |4 aut | |
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