Estimation of the basic reproduction number, average incubation time, asymptomatic infection rate, and case fatality rate for COVID-19 : Meta-analysis and sensitivity analysis
© 2020 Wiley Periodicals LLC..
The coronavirus disease-2019 (COVID-19) has been found to be caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, comprehensive knowledge of COVID-19 remains incomplete and many important features are still unknown. This manuscript conducts a meta-analysis and a sensitivity study to answer the questions: What is the basic reproduction number? How long is the incubation time of the disease on average? What portion of infections are asymptomatic? And ultimately, what is the case fatality rate? Our studies estimate the basic reproduction number to be 3.15 with the 95% CI (2.41-3.90), the average incubation time to be 5.08 days with the 95% CI (4.77-5.39) (in day), the asymptomatic infection rate to be 46% with the 95% CI (18.48%-73.60%), and the case fatality rate to be 2.72% with 95% CI (1.29%-4.16%) where asymptomatic infections are accounted for.
Errataetall: | |
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Medienart: |
E-Artikel |
Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:92 |
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Enthalten in: |
Journal of medical virology - 92(2020), 11 vom: 15. Nov., Seite 2543-2550 |
Sprache: |
Englisch |
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Beteiligte Personen: |
He, Wenqing [VerfasserIn] |
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Links: |
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Themen: |
Asymptomatic infection rate |
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Anmerkungen: |
Date Completed 24.12.2020 Date Revised 16.07.2022 published: Print-Electronic ErratumIn: J Med Virol. 2022 Jan;94(1):425. - PMID 34633667 Citation Status MEDLINE |
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doi: |
10.1002/jmv.26041 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM310506859 |
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520 | |a © 2020 Wiley Periodicals LLC. | ||
520 | |a The coronavirus disease-2019 (COVID-19) has been found to be caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, comprehensive knowledge of COVID-19 remains incomplete and many important features are still unknown. This manuscript conducts a meta-analysis and a sensitivity study to answer the questions: What is the basic reproduction number? How long is the incubation time of the disease on average? What portion of infections are asymptomatic? And ultimately, what is the case fatality rate? Our studies estimate the basic reproduction number to be 3.15 with the 95% CI (2.41-3.90), the average incubation time to be 5.08 days with the 95% CI (4.77-5.39) (in day), the asymptomatic infection rate to be 46% with the 95% CI (18.48%-73.60%), and the case fatality rate to be 2.72% with 95% CI (1.29%-4.16%) where asymptomatic infections are accounted for | ||
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