The diagnosis of SARS-CoV2 pneumonia : A review of laboratory and radiological testing results

© 2020 Wiley Periodicals LLC..

The rapid emergence of coronavirus disease 2019 (COVID-19) has necessitated the implementation of diverse pandemic control strategies throughout the world. To effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that disease spread will be slowed. At present, the diagnosis of this infectious form of coronavirus pneumonia is largely dependent upon a combination of laboratory testing and imaging analyses of variable diagnostic efficacy. In the present report, we reviewed prior literature pertaining to the diagnosis of different forms of pneumonia caused by coronaviruses (severe acute respiratory syndrome [SARS], Middle East respiratory syndrome, and SARS-CoV-2) and assessed two different potential diagnostic approaches. We ultimately found that computed tomography was associated with a higher rate of diagnostic accuracy than was a real-time quantitative polymerase chain reaction-based approach (P = .0041), and chest radiography (P = .0100). Even so, it is important that clinicians utilize a combination of laboratory and radiological testing where possible to ensure that this virus is reliably and quickly detected such that it may be treated and patients may be isolated in a timely fashion, thereby effectively curbing the further progression of this pandemic.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:92

Enthalten in:

Journal of medical virology - 92(2020), 11 vom: 28. Nov., Seite 2420-2428

Sprache:

Englisch

Beteiligte Personen:

Zheng, Zhong [VerfasserIn]
Yao, Zhixian [VerfasserIn]
Wu, Ke [VerfasserIn]
Zheng, Junhua [VerfasserIn]

Links:

Volltext

Themen:

Chest radiography
Computed tomography
Coronavirus disease 2019
Coronavirus pneumonia
Diagnosis
Journal Article
Polymerase chain reaction
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 24.12.2020

Date Revised 16.07.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1002/jmv.26081

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM31044683X