Mysterious Virus : A Review on Behavior and Treatment Approaches of the Novel Coronavirus, 2019-nCoV

Copyright © 2020 IMSS. Published by Elsevier Inc. All rights reserved..

At the end of the year 2019, the novel coronavirus (2019-nCoV) was spreading in Wuhan, China, and the outbreak process has a high speed. It was recognized as a pandemic by the World Health Organization (WHO) on 11 March 2020. Coronaviruses are enveloped and single-stranded RNA that have several families including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The pathogenesis mechanism and disease outcomes of SARS and MERS are now clear to some extent, but little information is available for 2019-nCoV. This newly identified corona virus infection represents flu-like symptoms, but usually the first symptoms are fever and dry cough. There has been no specific treatment against 2019-nCoV up to now, and physicians only apply supportive therapy. In the present article, we made an attempt to review the behavior of the virus around the world, epidemiology, a pathway for influx into the host cells, clinical presentation, as well as the treatments currently in use and future approaches; nitazoxanide may be our dream drug. We hope that this review has a positive impact on public knowledge for helping to deal with the 2019-nCoV and move one step forward toward its treatment in the near future.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:51

Enthalten in:

Archives of medical research - 51(2020), 5 vom: 01. Juli, Seite 375-383

Sprache:

Englisch

Beteiligte Personen:

Hemmati, Farshad [VerfasserIn]
Saedi, Samira [VerfasserIn]
Hemmati-Dinarvand, Mohsen [VerfasserIn]
Zarei, Marzie [VerfasserIn]
Seghatoleslam, Atefeh [VerfasserIn]

Links:

Volltext

Themen:

2019-nCoV
Infection
Journal Article
Nitazoxanide
Nitro Compounds
Novel coronavirus
Respiratory problem
Review
SOA12P041N
Thiazoles
Treatment approach

Anmerkungen:

Date Completed 01.07.2020

Date Revised 13.11.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.arcmed.2020.04.022

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM310306647