Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients
© 2020 Wiley Periodicals, Inc..
OBJECTIVE: To investigate olfactory dysfunction (OD) in patients with mild coronavirus disease 2019 (COVID-19) through patient-reported outcome questionnaires and objective psychophysical testing.
METHODS: COVID-19 patients with self-reported sudden-onset OD were recruited. Epidemiological and clinical data were collected. Nasal complaints were evaluated with the sinonasal outcome-22. Subjective olfactory and gustatory status was evaluated with the National Health and Nutrition Examination Survey. Objective OD was evaluated using psychophysical tests.
RESULTS: Eighty-six patients completed the study. The most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction (58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by 61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12 hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation between the objective test results and subjective reports of nasal obstruction or postnasal drip.
CONCLUSION: A significant proportion of COVID-19 patients reporting OD do not have OD on objective testing.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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| Enthalten in: |
Head & neck - 42(2020), 7 vom: 01. Juli, Seite 1583-1590 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Lechien, Jerome R [VerfasserIn] |
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| Links: |
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| Themen: |
Anosmia |
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| Anmerkungen: |
Date Completed 20.07.2020 Date Revised 18.12.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/hed.26279 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM310193184 |
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| 245 | 1 | 0 | |a Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients |
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| 500 | |a Date Revised 18.12.2020 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 Wiley Periodicals, Inc. | ||
| 520 | |a OBJECTIVE: To investigate olfactory dysfunction (OD) in patients with mild coronavirus disease 2019 (COVID-19) through patient-reported outcome questionnaires and objective psychophysical testing | ||
| 520 | |a METHODS: COVID-19 patients with self-reported sudden-onset OD were recruited. Epidemiological and clinical data were collected. Nasal complaints were evaluated with the sinonasal outcome-22. Subjective olfactory and gustatory status was evaluated with the National Health and Nutrition Examination Survey. Objective OD was evaluated using psychophysical tests | ||
| 520 | |a RESULTS: Eighty-six patients completed the study. The most common symptoms were fatigue (72.9%), headache (60.0%), nasal obstruction (58.6%), and postnasal drip (48.6%). Total loss of smell was self-reported by 61.4% of patients. Objective olfactory testings identified 41 anosmic (47.7%), 12 hyposmic (14.0%), and 33 normosmic (38.3%) patients. There was no correlation between the objective test results and subjective reports of nasal obstruction or postnasal drip | ||
| 520 | |a CONCLUSION: A significant proportion of COVID-19 patients reporting OD do not have OD on objective testing | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Chiesa-Estomba, Carlos M |e verfasserin |4 aut | |
| 700 | 1 | |a Khalife, Mohamad |e verfasserin |4 aut | |
| 700 | 1 | |a Hans, Stéphane |e verfasserin |4 aut | |
| 700 | 1 | |a Calvo-Henriquez, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Martiny, Delphine |e verfasserin |4 aut | |
| 700 | 1 | |a Journe, Fabrice |e verfasserin |4 aut | |
| 700 | 1 | |a Sowerby, Leigh |e verfasserin |4 aut | |
| 700 | 1 | |a Saussez, Sven |e verfasserin |4 aut | |
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