Clinical features of coronavirus disease 2019 in children aged <18 years in Jiangxi, China : an analysis of 23 cases
OBJECTIVE: To study the clinical features of coronavirus disease 2019 (COVID-19) in children aged <18 years.
METHODS: A retrospective analysis was performed from the medical data of 23 children, aged from 3 months to 17 years and 8 months, who were diagnosed with COVID-19 in Jiangxi, China from January 21 to February 29, 2020.
RESULTS: Of the 23 children with COVID-19, 17 had family aggregation. Three children (13%) had asymptomatic infection, 6 (26%) had mild type, and 14 (61%) had common type. Among these 23 children, 16 (70%) had fever, 11 (48%) had cough, 8 (35%) had fever and cough, and 8 (35%) had wet rales in the lungs. The period from disease onset or the first nucleic acid-positive detection of SARS-CoV-2 to the virus nucleic acid negative conversion was 6-24 days (median 12 days). Of the 23 children, 3 had a reduction in total leukocyte count, 2 had a reduction in lymphocytes, 2 had an increase in C-reactive protein, and 2 had an increase in D-dimer. Abnormal pulmonary CT findings were observed in 12 children, among whom 9 had patchy ground-glass opacities in both lungs. All 23 children received antiviral therapy and were recovered.
CONCLUSIONS: COVID-19 in children aged <18 years often occurs with family aggregation, with no specific clinical manifestation and laboratory examination results. Most of these children have mild symptoms and a good prognosis. Epidemiological history is of particular importance in the diagnosis of COVID-19 in children aged <18 years.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:22 |
|---|---|
| Enthalten in: |
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 22(2020), 5 vom: 21. Mai, Seite 419-424 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Wu, Hua-Ping [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 26.05.2020 Date Revised 11.11.2023 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM310169658 |
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| 100 | 1 | |a Wu, Hua-Ping |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical features of coronavirus disease 2019 in children aged <18 years in Jiangxi, China |b an analysis of 23 cases |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 26.05.2020 | ||
| 500 | |a Date Revised 11.11.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To study the clinical features of coronavirus disease 2019 (COVID-19) in children aged <18 years | ||
| 520 | |a METHODS: A retrospective analysis was performed from the medical data of 23 children, aged from 3 months to 17 years and 8 months, who were diagnosed with COVID-19 in Jiangxi, China from January 21 to February 29, 2020 | ||
| 520 | |a RESULTS: Of the 23 children with COVID-19, 17 had family aggregation. Three children (13%) had asymptomatic infection, 6 (26%) had mild type, and 14 (61%) had common type. Among these 23 children, 16 (70%) had fever, 11 (48%) had cough, 8 (35%) had fever and cough, and 8 (35%) had wet rales in the lungs. The period from disease onset or the first nucleic acid-positive detection of SARS-CoV-2 to the virus nucleic acid negative conversion was 6-24 days (median 12 days). Of the 23 children, 3 had a reduction in total leukocyte count, 2 had a reduction in lymphocytes, 2 had an increase in C-reactive protein, and 2 had an increase in D-dimer. Abnormal pulmonary CT findings were observed in 12 children, among whom 9 had patchy ground-glass opacities in both lungs. All 23 children received antiviral therapy and were recovered | ||
| 520 | |a CONCLUSIONS: COVID-19 in children aged <18 years often occurs with family aggregation, with no specific clinical manifestation and laboratory examination results. Most of these children have mild symptoms and a good prognosis. Epidemiological history is of particular importance in the diagnosis of COVID-19 in children aged <18 years | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Li, Bing-Fei |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Xiao |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Hua-Zhu |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Shu-Ai |e verfasserin |4 aut | |
| 700 | 1 | |a Cheng, Hao |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, Xin-He |e verfasserin |4 aut | |
| 700 | 1 | |a Tang, Jian-Xin |e verfasserin |4 aut | |
| 700 | 1 | |a Zhong, Fu-Chu |e verfasserin |4 aut | |
| 700 | 1 | |a Zeng, Ling-Wen |e verfasserin |4 aut | |
| 700 | 1 | |a Yu, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Yuan, Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Xian-Fei |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yu-Ping |e verfasserin |4 aut | |
| 700 | 1 | |a Zheng, Zong-Li |e verfasserin |4 aut | |
| 700 | 1 | |a Pan, Tian-Bo |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Zhi-Xing |e verfasserin |4 aut | |
| 700 | 1 | |a Yuan, Jin-Feng |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Qiang |e verfasserin |4 aut | |
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