Mice with humanized-lungs and immune system - an idealized model for COVID-19 and other respiratory illness
Lack of an appropriate animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for COVID-19 pandemic disease, represents a significant hurdle in the process of understanding disease biology and evaluating therapeutic and preventive candidates. It is time for public health agencies to revisit regulation on transplantation of human pluripotent stem cells for the possibility of the development of a humanized mice model with a humanized lung.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Virulence - 11(2020), 1 vom: 22. Dez., Seite 486-488 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Pujhari, Sujit [VerfasserIn] |
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| Links: |
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| Themen: |
Animal model |
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| Anmerkungen: |
Date Completed 22.05.2020 Date Revised 30.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1080/21505594.2020.1763637 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Lack of an appropriate animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent responsible for COVID-19 pandemic disease, represents a significant hurdle in the process of understanding disease biology and evaluating therapeutic and preventive candidates. It is time for public health agencies to revisit regulation on transplantation of human pluripotent stem cells for the possibility of the development of a humanized mice model with a humanized lung | ||
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