Comparison of psoriasis guidelines for use of apremilast in the United States and Europe : a critical appraisal and comprehensive review

PURPOSE: This review article serves to compare global dermatologic organizations and the available clinical practice guidelines for the use of apremilast in the treatment of psoriasis.

MATERIALS AND METHODS: Guidelines from the American Academy of Dermatology (AAD), the National Psoriasis Foundation (NPF), the European S3, the National Institute for Health and Care Excellence (NICE), the French Society of Dermatology (SFD), the Swiss S1, and Italy were reviewed and compared.

RESULTS: Of the American and European guidelines available for use of apremilast, several organizations are in agreement regarding the dosage of apremilast, but there are significant disagreements concerning matters such as medication indication, pretreatment laboratory testing, and contraindications to therapy.

CONCLUSION: Apremilast is an effective and well-tolerated treatment option for patients with psoriasis and should be considered in the line of therapy that dermatologists discuss with their patients, especially those with contraindications to other systemic therapies such as biologics. Consideration should be given to the evidence-based recommendations of global dermatology organizations to help guide therapeutic decisions.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

The Journal of dermatological treatment - 33(2022), 1 vom: 02. Feb., Seite 94-99

Sprache:

Englisch

Beteiligte Personen:

Ghamrawi, Rima I [VerfasserIn]
Ghiam, Neda [VerfasserIn]
Wu, Jashin J [VerfasserIn]

Links:

Volltext

Themen:

4Z8R6ORS6L
Anti-Inflammatory Agents, Non-Steroidal
Apremilast
Biological Products
Clinical practice guidelines
Journal Article
Phosphodiesterase 4 inhibitor
Psoriasis
Review
Thalidomide
UP7QBP99PN

Anmerkungen:

Date Completed 15.02.2022

Date Revised 01.05.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/09546634.2020.1770176

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM310021669