Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs

In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conventional disease-modifying antirheumatic drugs (cDMARDs). The patient presented with a 4-day history of myalgia and febrile sensation. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). Chest X-ray showed increased opacity on the right lower lung area, and C-reactive protein level was slightly elevated. The patient was treated with antiviral agents (lopinavir/ritonavir), and treatment with cDMARDs was discontinued except hydroxychloroquine. Her symptoms and laboratory results gradually improved. Three weeks later, real-time PCR for COVID-19 showed negative conversion, and the patient was discharged without any complications.

Media Type:

Electronic Article

Year of Publication:

2020

Contained In:

Rheumatology international - Vol. 40, No. 6 (2020), p. 991-995

Language:

English

Contributors:

Song, Jehun
Kang, Seongmin
Choi, Seung Won
Seo, Kwang Won
Lee, Sunggun
So, Min Wook
Lim, Doo-Ho

Links:

Volltext

Keywords:

2494G1JF75
4QWG6N8QKH
Antirheumatic Agents
Arthritis, Rheumatoid
COVID-19
Case Reports
China
Coronavirus
Coronavirus Infections
Disease-modifying antirheumatic drugs
Drug Combinations
Female
Humans
Hydroxychloroquine
Immunocompromised Host
Journal Article
Lopinavir
Lopinavir-ritonavir drug combination
Middle Aged
O3J8G9O825
Pandemics
Pneumonia
Pneumonia, Viral
Real-Time Polymerase Chain Reaction
Rheumatoid arthritis
Ritonavir
Treatment Outcome

Notes:

Date Completed 04.05.2020

Date Revised 09.09.2020

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1007/s00296-020-04584-7

PMID:

32314010

PPN (Catalogue-ID):

NLM309838886