Nano-hydroxyapatite use in dentistry : a systematic review

Nano-hydroxyapatite (nano-HA) is a material with multiple uses due to its biocompatibility and its resemblance to the nonorganic bone structure. It is used in various dental domains such as implantology, surgery, periodontology, esthetics and prevention. The aim of this study is to provide a wide understanding of nano-HA and to promote treatments based on nanomaterials in dentistry. A search in two data bases, Scopus, and PubMED, was conducted over a 5 years period. We chose a 5 years period because this revealed the most recent published studies with the key words 'nano-HA' and 'dentistry'. A number of 32 studies were included in this systematic review. In implantology the main use of nano-HA was as a coating material for titanium implants and its effect was assessed in the matter of osteointegration and inflammatory response as well as antibacterial activity. In tissue engineering the use of nano-HA was directed to surgery and periodontology and this material was assessed mainly as a grafting material. In esthetics and prevention its use was mainly focused on dentinal hypersensitivity treatment, remineralizing potential and as bleaching co-agent. Nano-HA is a relatively novel material with outstanding physical, chemical, mechanical and biological properties that makes it suitable for multiple interventions. It outperformed most of the classic materials used in implantology and surgery but it should be further investigated for bone engineering and caries prevention therapy.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:52

Enthalten in:

Drug metabolism reviews - 52(2020), 2 vom: 28. Mai, Seite 319-332

Sprache:

Englisch

Beteiligte Personen:

Bordea, Ioana Roxana [VerfasserIn]
Candrea, Sebastian [VerfasserIn]
Alexescu, Gabriela Teodora [VerfasserIn]
Bran, Simion [VerfasserIn]
Băciuț, Mihaela [VerfasserIn]
Băciuț, Grigore [VerfasserIn]
Lucaciu, Ondine [VerfasserIn]
Dinu, Cristian Mihail [VerfasserIn]
Todea, Doina Adina [VerfasserIn]

Links:

Volltext

Themen:

Dental Materials
Esthetics
Hydroxyapatites
Implantology
Journal Article
Nano-hydroxyapatite
Prevention
Systematic Review
Tissue engineering

Anmerkungen:

Date Completed 12.01.2021

Date Revised 12.01.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/03602532.2020.1758713

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM309762251