Chloroquine as a possible treatment for COVID-19
Since the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:164 |
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| Enthalten in: |
Nederlands tijdschrift voor geneeskunde - 164(2020) vom: 11. März |
| Sprache: |
Niederländisch |
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| Weiterer Titel: |
Chloroquine als mogelijke behandeling van COVID-19 |
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| Beteiligte Personen: |
Coumou, Jeroen [VerfasserIn] |
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| Themen: |
2494G1JF75 |
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| Anmerkungen: |
Date Completed 20.05.2020 Date Revised 18.12.2020 published: Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM309751683 |
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| 520 | |a Since the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19 | ||
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