Prevalence and Mechanisms of Carbapenem Resistance in Klebsiella pneumoniae and Escherichia coli : A Systematic Review and Meta-Analysis of Cross-Sectional Studies from Iran
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) represents an urgent threat worldwide. We aimed to investigate the frequency of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli in Iran. Materials and Methods: PubMed/Medline, Embase, Scopus, Web of Sciences, and Iranian databases were searched to find potentially relevant articles. Statistical analyses were performed using STATA version 14. Results: Forty-nine studies fulfilled the inclusion criteria. The pooled rates of resistance to carbapenem in K. pneumoniae and E. coli were 24.0% (95% confidence interval [CI] 18.0-31.0) and 5.0% (95% CI 2.0-8.0), respectively. blaOXA-48 gene was the most common cause of carbapenem resistance in K. pneumoniae and E. coli. Conclusions: CRE is prevalent in Iran, which confers the importance of strength prevention and control measures.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Microbial drug resistance (Larchmont, N.Y.) - 26(2020), 12 vom: 15. Dez., Seite 1491-1502 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Nasiri, Mohammad Javad [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Bacterial Agents |
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| Anmerkungen: |
Date Completed 08.09.2021 Date Revised 08.09.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1089/mdr.2019.0440 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM30932534X |
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| 520 | |a Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) represents an urgent threat worldwide. We aimed to investigate the frequency of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli in Iran. Materials and Methods: PubMed/Medline, Embase, Scopus, Web of Sciences, and Iranian databases were searched to find potentially relevant articles. Statistical analyses were performed using STATA version 14. Results: Forty-nine studies fulfilled the inclusion criteria. The pooled rates of resistance to carbapenem in K. pneumoniae and E. coli were 24.0% (95% confidence interval [CI] 18.0-31.0) and 5.0% (95% CI 2.0-8.0), respectively. blaOXA-48 gene was the most common cause of carbapenem resistance in K. pneumoniae and E. coli. Conclusions: CRE is prevalent in Iran, which confers the importance of strength prevention and control measures | ||
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| 700 | 1 | |a Arshadi, Mania |e verfasserin |4 aut | |
| 700 | 1 | |a Fardsanei, Fatemeh |e verfasserin |4 aut | |
| 700 | 1 | |a Deihim, Behnaz |e verfasserin |4 aut | |
| 700 | 1 | |a Davoudabadi, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Zamani, Samin |e verfasserin |4 aut | |
| 700 | 1 | |a Hajikhani, Bahareh |e verfasserin |4 aut | |
| 700 | 1 | |a Goudarzi, Hossein |e verfasserin |4 aut | |
| 700 | 1 | |a Goudarzi, Mehdi |e verfasserin |4 aut | |
| 700 | 1 | |a Seghatoleslami, Zahra Sadat |e verfasserin |4 aut | |
| 700 | 1 | |a Dabiri, Hossein |e verfasserin |4 aut | |
| 700 | 1 | |a Tabarsi, Payam |e verfasserin |4 aut | |
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