Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs

In December 2019, numerous coronavirus disease 2019 (COVID-19) cases were reported in Wuhan, China, which has since spread throughout the world. However, its impact on rheumatoid arthritis (RA) patients is unknown. Herein, we report a case of COVID-19 pneumonia in a 61-year-old female RA patient who was receiving conventional disease-modifying antirheumatic drugs (cDMARDs). The patient presented with a 4-day history of myalgia and febrile sensation. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). Chest X-ray showed increased opacity on the right lower lung area, and C-reactive protein level was slightly elevated. The patient was treated with antiviral agents (lopinavir/ritonavir), and treatment with cDMARDs was discontinued except hydroxychloroquine. Her symptoms and laboratory results gradually improved. Three weeks later, real-time PCR for COVID-19 showed negative conversion, and the patient was discharged without any complications.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:40

Enthalten in:

Rheumatology international - 40(2020), 6 vom: 22. Juni, Seite 991-995

Sprache:

Englisch

Beteiligte Personen:

Song, Jehun [VerfasserIn]
Kang, Seongmin [VerfasserIn]
Choi, Seung Won [VerfasserIn]
Seo, Kwang Won [VerfasserIn]
Lee, Sunggun [VerfasserIn]
So, Min Wook [VerfasserIn]
Lim, Doo-Ho [VerfasserIn]

Links:

Volltext

Themen:

2494G1JF75
4QWG6N8QKH
Antirheumatic Agents
COVID-19
Case Reports
Coronavirus
Disease-modifying antirheumatic drugs
Drug Combinations
Hydroxychloroquine
Journal Article
Lopinavir
Lopinavir-ritonavir drug combination
O3J8G9O825
Pneumonia
Rheumatoid arthritis
Ritonavir

Anmerkungen:

Date Completed 04.05.2020

Date Revised 18.12.2020

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s00296-020-04584-7

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM308984757