Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications : a review

© 2019 Elsevier Ltd. All rights reserved..

Schiff bases are versatile organic compounds which are widely used and synthesized by condensation reaction of different amino compound with aldehydes or ketones known as imine. Schiff base ligands are considered as privileged ligands as they are simply synthesized by condensation. They show broad range of application in medicine, pharmacy, coordination chemistry, biological activities, industries, food packages, dyes, and polymer and also used as an O2 detector. Semicarbazone is an imine derivative which is derived from condensation of semicarbazide and suitable aldehyde and ketone. Imine ligand-containing transition metal complexes such as copper, zinc, and cadmium have shown to be excellent precursors for synthesis of metal or metal chalcogenide nanoparticles. In recent years, the researchers have attracted enormous attention toward Schiff bases, semicarbazones, thiosemicarbazones, and their metal complexes owing to numerous applications in pharmacology such as antiviral, antifungal, antimicrobial, antimalarial, antituberculosis, anticancer, anti-HIV, catalytic application in oxidation of organic compounds, and nanotechnology. In this review, we summarize the synthesis, structural, biological, and catalytic application of Schiff bases as well as their metal complexes.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:14

Enthalten in:

Materials today. Chemistry - 14(2019) vom: 13. Dez., Seite 100195

Sprache:

Englisch

Beteiligte Personen:

More, M S [VerfasserIn]
Joshi, P G [VerfasserIn]
Mishra, Y K [VerfasserIn]
Khanna, P K [VerfasserIn]

Links:

Volltext

Themen:

2,6-DAPBPTSC, 2,6-diacetylpyridine bis-4-phenyl-3-thiosemicarbazone
35-DTBP, 3,5-di-tert-butylphenol
3CLpro, 3C-like protease
ATNR, Amine terminated liquid natural rubber
ATT, 2-acetylthiophene thiosemicarbazone
BBPT, Biacetyl bis(4-phenyl-3-thiosemicarbazone)
BBTSC, Benzyloxybenzaldehyde thiosemicarbazone
BCG, Bacillus calmette-guérine
BDT, Benzyldithiosemicarbazone
BGPT, Bipyridyl glyoxal bis(4-phenyl-3-thiosemicarbazone)
BMTS, Biacetyl monothiosemicarbazone
Biological/biomedical activities
Bipy, 2,2-bipyridine
CT DNA, Calf thymus deoxyribonucleic acid
DAPY, 2,3-diamino-pyridine
DTBP, 2,6-di-tert-butylphenol
DTBQ, 2,6-di-tert-butyl-4,4′-benzoquinone
EAC, Enrichlish Ascitices Cells
HEK-293, Human Embryonic Kidney cells
HL-60, Human leukemia-60 cell line
HeLa, immortal cell lines
HepG2, Hepatic cellular carcinoma cells (Human liver cancer cell line)
IgG, Immunoglobin G
Journal Article
K B HCT-8, Human colon cancer cell line
M-IBDET, N-methylisatin-β-4′,4′-diethylthiosemicarbazone
MCF-7, Michigan Cancer Foundation-7
MCF7 cells, Michigan Cancer Foundation-7 (breast cancer cell line)
MHV, Mouse hepatitis virus
MLV, Moloney leukemia virus
MSOPD, N,N-bis(3-methylsalicylidene)-ortho-phenylenediamine
Metal complexes
NQSC, Naphthoquinone semicarbazone
NQTS, ortho-Naphthoquinone thiosemicarbazone
OLED, Organic light emitting diode
PAS, p-amino salicylic acid
PPTS, Picolinealdehyde-4-phenyl-3-thiosemicarbazone
Phen, 1,10-phenanthroline
SARS, Severe acute respiratory syndrome
SARS CoV, Severe Acute Respiratory Syndrome coronavirus
SB-HAG, Schiff bases of hydroxyamino guanidines
SK-MEL-30, Human Melanoma Cell Line
SK-OV-3 cells, Ovarian cancer cell line
SSB-HAG, salicylaldehyde Schiff bases of HAG
ScCO2, Super-critical carbon dioxide
Schiff base
Semicarbazone
TCIDw, Tissue culture Infective Dose
TTBDQ, 3,5,3′,5′-tetra-tert-butyl-4,4′-diphenoquinone
VSV, vesicular stomatitis virus

Anmerkungen:

Date Revised 13.11.2023

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.mtchem.2019.100195

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM308741102